In this paper, the detailed study of magnetic properties of Dy3+ substituted soft manganese ferrite (MnFe2O4) nanoparticles with varied contents of Dy3+ ions (0.00 ≤ x ≤ 0.16) was carried out by vibrating sample magnetometery (VSM) at room temperature. The synthesis of reported magnetic materials was carried out via facile wet chemical route. Structural characterization was investigated via X-ray diffraction and infra-red spectroscopy. Exploration of magnetic measurements revealed an irregular behavior in the values of saturation magnetization (Ms), remanent magnetization (Mr), and coercivity (Hc) depending upon the concentration of rare-earth ions (Dy3+). The fluctuations in the values of Ms, Mr, and Hc may be associated with the modifications in the spin-exchange interactions caused by structural changes due to the substitution of rare-earth ions (Dy3+). DC electrical resistivity values were recorded and were found to be increased with increased Dy3+ contents. The soft magnetic nature of Dy3+ substituted MnFe2O4 spinel ferrites nanoparticles suggested their possible utilization in switching mode power supplies, recording media, spintronics, and many other advanced technological devices.