Study of the value of CPK and LDH isoenzymedeterminations in the differential diagnosis of ischemic chest pain

Fröhlich, Jiří; Brosseuk, A.; Grant, Angela; McLennan, Meghan

doi:10.1016/s0009-9120(78)80015-0

Cited by 5 publications

(1 citation statement)

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“…We do not yet routinely measure creatine kinase isoenzyme (CK-MB), but when we do, a supplementary lest will be needed for the patients who are admitted more thaii 24 h after their myocardial infarction, when CK-MB may have normalized (8)(9)(10)(11)(12). In the present study, this was the case for 9 out of 49 patients.…”

Section: Discussionmentioning

confidence: 78%

Lactate Dehydrogenase Isoenzyme 1 in the Diagnosis of Myocardial Infarction

Fogh-Andersen¹,

Sørensen²,

Møller-Petersen³

et al. 1982

CCLM

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Summary:A new immunochemical method for the measurement of lactate dehydrogenase isoenzyme l (LDH-1) was used on 113 consecutively admitted patients with suspected myocardial infarction. Using WHO's criteria and our routine program 49 were classified äs having myocardial infarction and 64 äs having no myocardial infarction. LDH-1 was better than total lactate dehydrogenase in discriminating between patients with and without myocardial infarction (p < 0.02), and the efficiency (the number of correct classifications divided by the total number of analyses) on day 2-3 equalled that from the literature for CK-MB on day 1. Total lactate dehydrogenase and LDH-1 are supplemental to creatine kinase (CK) and CK-MB, while aspartate aminotransferase may be omitted in the diagnosis of myocardial infarction. Determination of the ratio of LDH-1 to total lactate dehydrogenase qffered no advantage.

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Section: Discussionmentioning

confidence: 78%