Study of the Reactivity of 6,8‐Dimethyl‐4‐oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde Towards Amino‐6‐oxopyridine‐3‐carboxylate Derivatives

Abstract

The condensation reactions of 6,8‐dimethyl‐4‐oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde (1) with equimolar amounts of ethyl 2‐amino‐4‐(4‐chlorophenyl)‐5‐cyano‐1‐[(5,6‐diphenyl‐1,2,4‐triazin‐3‐yl)amino]‐6‐oxo‐1,6‐dihydropyridine‐3‐carboxylate (2) at different reaction conditions gave different chromanone and chromenone products 3, 4, 5. Also, the condensation reactions of compound 1 with ethyl 5‐cyano‐1,2‐diamino‐4‐(3‐nitrophenyl)‐6‐oxo‐1,6‐dihydropyridine‐3‐carboxylate (6) in absolute ethanol, dry benzene, acetic acid, and/or dry xylene gave a variety of products 7, 8, 9, 10 depending on the solvent used.