Study of the Products of Iodocyclization of 4-Allyl-5-phenyl-1,2,4-triazole-3-thione

[1,3]Thiazolo[2′,3′:3,4][1,2,4]triazolo[1,5‐a]pyrimidines – A New Heterocyclic System Accessed via Bromocyclization

“…In recent years, heteroannulation processes based on electrophilic halocyclization has proved to be useful in producing various heterocycles: furane , pyrrole , selenophene , pyrazole , piperazine , indole , quinoline , imidazothiazole , imidazotriazine , and thiazolo(oxazolo‐)thienopyrimidine . For example, [1,3]thiazolo[1,2,4]triazoles formation was reported to be due to electrophilic heterocyclization of monoalkenyl‐substituted [1,2,4]triazolethiones affected by halogens and mineral acids . On this basis, we reasoned that introduction of an allyl group into [1,3]thiazolo[1,2,4]triazole system could be a convenient way to developing new annulation reactions.…”