Study of the Prevalence of Microalbuminuria in Patients of Essential Hypertension and its Correlation with Left Ventricular Hypertrophy and Carotid Artery Intima-media Thickness

Maggon, Rita Rani; Malik, Rupali; Jain, Nutan; Isser, HS

doi:10.4103/jcpc.jcpc_22_17

Cited by 7 publications

(5 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In present study out of 102 patients, males were 62 and females were 40. Maggon et al [9] . determined the prevalence of MA in hypertensive patients and to examine its correlation with severity of hypertension, left ventricular hypertrophy (LVH), and common carotid intima-media thickness (CCIMT).…”

Section: Discussionmentioning

confidence: 98%

Prevalence of microalbuminuria in patients with essential hypertension- A clinical study

Goyal¹

2020

Int. J. Adv. Res. Med.

View full text Add to dashboard Cite

Background: The present study was conducted to record prevalence of Microalbuminuria in patients with essential hypertension. Materials & Methods:The present study was conducted on 102 patients of diagnosed essential hypertension of both genders. Microalbuminuria was measured in all patients in a 24h urinary sample. Results: Out of 102 patients, males were 62 and females were 40. Out of 102 patients, microalbuminuria was present in 40 patients. Maximum cases were seen in age group >70 years (20) followed by 6-70 years ( 14), 50-60 years (4) and 40-50 years (2). Conclusion: Authors found the presence of microalbuminuria in a significant number of newly detected and untreated patients of essential hypertension.

show abstract

Section: Discussionmentioning

confidence: 98%

Prevalence of microalbuminuria in patients with essential hypertension- A clinical study

Goyal¹

2020

Int. J. Adv. Res. Med.

View full text Add to dashboard Cite

show abstract

“…Among 28 patients without MA, only 7 patients had LVH. Thus, it showed a significant positive relation between MA and LVH (p value 0.004) 9.…”

mentioning

confidence: 87%

Microalbuminuria as a predictor of cardiovascular morbidity in essential hypertensive patients: research study done at tertiary care centre in Western India

2021

View full text Add to dashboard Cite

Background:Small amount of albumin excretion in urine, termed as microalbuminuria, has been postulated to be an indicator of endothelial dysfunction. This study was done to find the prevalence of microalbuminuria in patients with essential hypertension and to study the association of microalbuminuria with cardiovascular morbidity.Methods:This cross-sectional, observational study was conducted at the Department of Internal Medicine, Medical College and SSG Hospital, Baroda; by selecting 60 first time detected essential hypertensive patients, without any significant past or treatment history, attending Medicine outpatient department (OPD) or admitted in different wards at SSG hospital, for various reasons. A detailed history, clinical examination, basic blood investigation, urine albumin to creatinine ratio, electrocardiography (ECG) and 2D echo were done in all patients.Results:In this study, microalbuminuria was found in 24 (40%) cases with prevalence increasing with increasing age. A higher serum cholesterol, serum low density lipoprotein (LDL) and cholesterol/high density lipoprotein (HDL) ratio; left ventricular hypertrophy (LVH), ST-T changes and bundle branch block on ECG; LVH, hypokinesia and diastolic dysfunction on 2D echo; retinopathy on D fundus examination were all associated with higher microalbumin excretion in urine. Microalbuminuria was independent of age, sex, addiction to smoking, alcohol, BMI and severity/stage of hypertension. Thus, irrespective of existing known cardiovascular risk factors, microalbuminuria was associated with signs of cardiovascular morbidity.Conclusions:As a predictor of systemic vascular dysfunction, microalbuminuria can be used to stratify and prognosticate hypertensive patients at a higher risk of developing further vascular complications and they can be screened early for same.

show abstract

“…The prevalence of microalbuminuria in hypertensive patients was reported to be 6%-42% in previous studies [13][14][15][16][17][18] . Maggon RR et al [18] conducted a study on 50 patients with essential hypertension and found a 44% prevalence of microalbuminuria. In our study prevalence of raised UACR was 70% which was higher compared to previous studies.…”

Section: Uacrmentioning

confidence: 99%

UACR: A novel risk marker for early detection of Atherosclerotic cardiovascular disease

Pragya¹,

Yadav²,

Sud³

et al. 2023

GSC Adv. Res. Rev.

View full text Add to dashboard Cite

Background: Hypertension is leading and modifiable risk factor for cardiovascular diseases and all-cause mortality. Left ventricular hypertrophy, seen in hypertensive patients is a strong predictor of unfavourable cardiovascular events. Microalbuminuria is considered as principal predictor of cardiovascular complications and mortality. Our study aims at finding prevalence of increased urine albumin creatinine ratio and left ventricular mass index in newly diagnosed hypertensive patients and finding a correlation among them. Methodology: A hospital based cross sectional study was done. Adult patients visiting hospital OPD were screened for primary hypertension as per AHA (2017) guidelines and 40 were included in study. All patients underwent relevant blood and urine investigations. Urine albumin creatinine ratio was calculated in spot urine sample and left ventricular mass index was calculated using 2-D echocardiography. Result: This study demonstrated that 70% newly diagnosed hypertensive patients had raised urine albumin creatinine ratio and 75% had raised left ventricular mass index. The data was plotted on scatter plot, which depicted the correlation between LVMI (g/m²) and UACR (mg/g). Non-parametric tests (Spearman Correlation) were used to explore the correlation between the two variables and strong positive correlation was found between LVMI (g/m²) and UACR (mg/g), and this correlation was statistically significant (rho = 0.74, p = <0.001). It has been found that for every 1 unit increase in LVMI (g/m²), the UACR (mg/g) increases by 2.58 units. Conversely, for every 1 unit increase in UACR (mg/g), the LVMI (g/m²) increases by 0.05 units. Conclusion: This study demonstrated the presence of microalbuminuria and evidence of left ventricular hypertrophy in a significant number of newly detected and untreated patients of essential hypertension. Also, there is significant association between LVMI and UACR (microalbuminuria) in hypertensive patients. Hence, we can recommend microalbuminuria as a screening tool for Left Ventricular Hypertrophy in newly diagnosed hypertensive patients so as to detect risk for cardiovascular events early and select our treatment strategy accordingly.

show abstract

Study of the Prevalence of Microalbuminuria in Patients of Essential Hypertension and its Correlation with Left Ventricular Hypertrophy and Carotid Artery Intima-media Thickness

Cited by 7 publications

References 1 publication

Prevalence of microalbuminuria in patients with essential hypertension- A clinical study

Prevalence of microalbuminuria in patients with essential hypertension- A clinical study

Microalbuminuria as a predictor of cardiovascular morbidity in essential hypertensive patients: research study done at tertiary care centre in Western India

UACR: A novel risk marker for early detection of Atherosclerotic cardiovascular disease

Contact Info

Product

Resources

About