Study of the interpolyelectrolyte reaction between chitosan and carboxymethyl cellulose

Argüelles‐Monal, Waldo; Covas, Carlos Peniche

doi:10.1002/marc.1988.030091004

Cited by 62 publications

(15 citation statements)

References 3 publications

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“…The values of degree of complexation obtained in the present work for the CHI/ALG complex are higher than those of the CHI/CMC PEC (θ = 0.13) [16], but much lower than the one obtained for the complex between chitosan and polygalacturonic acid (θ = 0.80) [15]. This indicates that substantial variations in the degree of complexation of chitosan PECs can be found in dependence of the nature of the polyanion.…”

Section: Influence Of the Composition Of Alginate On The Degree Of Cocontrasting

confidence: 72%

Study of the interpolyelectrolyte reaction between chitosan and alginate: influence of alginate composition and chitosan molecular weight

Becherán-Marón

Péniche

Argüelles‐Monal³

2004

International Journal of Biological Macromolecules

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Section: Influence Of the Composition Of Alginate On The Degree Of Cocontrasting

confidence: 72%

Study of the interpolyelectrolyte reaction between chitosan and alginate: influence of alginate composition and chitosan molecular weight

Becherán-Marón

Péniche

Argüelles‐Monal³

2004

International Journal of Biological Macromolecules

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“…Chitosan spectrum exhibited the distinctive absorption bands at 1658 cm -1 (Amide I), 1595 cm -1 (-NH 2 bending) and 1314 cm -1 (Amide III). The absorption bands at 1154 cm -1 (anti-symmetric stretching of the C-O-C bridge), 1082 and 1032 cm -1 (skeletal vibrations involving the C-O stretching) are characteristic of its saccharide structure [29].…”

Section: Synthesis and Spectral Characterizationmentioning

confidence: 99%

Interpenetrated Chitosan-Poly(Acrylic Acid-Co-Acrylamide) Hydrogels. Synthesis, Characterization and Sustained Protein Release Studies

Povea¹,

Argüelles‐Monal²,

Cauich-Rodríguez³

et al. 2011

MSA

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Interpenetrated polymer networks of chitosan (CHI), polyacrylic acid (PAA) and polyacrylamide (PAM) were prepared by free radical polymerization. These hydrogels were either washed with double distilled water (CHI/PAA/PAM) A or hydrolyzed with 1M sodium hydroxide (NaOH), (CHI/PAA/PAM) S. Both types of hydrogels were characterized by infrared spectroscopy, microstructural techniques and compressive mechanical testing. Finally, hydrogels were loaded with bovine serum albumin (BSA) and release followed at different pHs. Infrared spectra analysis showed correspondence between hydrogels and monomer feed compositions. Hydrolyzed hydrogels, had increased water content and pH swelling dependence. Compression modulus of swelled hydrolyzed hydrogels decreased with increasing equilibrium water content. Higher BSA loadings were achieved on hydrolyzed hydrogels due to their high water content and porosity. Protein release from hydrogels was low ( 20% after 10 hours) at pH 1.2, but sustained release was observed at pH 6.8 and 7.4. The integrity of the protein released at 6.8 and 7.4 by hydrolyzed hydrogels was unaffected. The hydrogles showed no cytotoxic effects on human skin dermal fibroblasts as determined by MTT assay except for two compositions of (CHI/PAA/PAM) A samples, which after seven days presented a viability lower than 80% respect to the control.

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“…¼ 20.1% determined by 1 H NMR, M v ¼ 2 Â 10 5 ) was obtained from shells of lobsters (Panulirus argus) as described elsewhere. [16] Chitosan flakes were dissolved in aqueous acetic acid, filtered, and precipitated with aqueous NaOH. The precipitated gel was washed several times with water and vacuum dried in a desiccator.…”

Section: Experimental Partmentioning

confidence: 99%

Drug Delivery Systems Based on Porous Chitosan/Polyacrylic acid Microspheres

Péniche

Fernández

Gallardo

et al. 2003

Macromolecular Bioscience

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Porous microspheres have been prepared by suspension free radical polymerization of acrylic acid (AA) in the presence of chitosan (CHI). The microspheres were characterized by FTIR and environmental SEM. The PAA content of the microspheres was estimated to be in the range 45–50 wt.‐%. The swelling degree of these particles is almost constant in the range 2 < pH < 5, but it increases considerably as the pH is raised from 5 to 10. The release profiles of microspheres loaded with meclofenamic acid (MF) were determined at pH 2, 7.4, and 10. The in vitro release of MF at different pHs was modulated by the solubility of the drug. These microcapsules are biodegradable and presented good biocompatibility and biodegradability during in vivo experiments.ESEM microphotograph of the porous PAA/CHI microspheres.magnified imageESEM microphotograph of the porous PAA/CHI microspheres.

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Study of the interpolyelectrolyte reaction between chitosan and carboxymethyl cellulose

Cited by 62 publications

References 3 publications

Study of the interpolyelectrolyte reaction between chitosan and alginate: influence of alginate composition and chitosan molecular weight

Study of the interpolyelectrolyte reaction between chitosan and alginate: influence of alginate composition and chitosan molecular weight

Interpenetrated Chitosan-Poly(Acrylic Acid-Co-Acrylamide) Hydrogels. Synthesis, Characterization and Sustained Protein Release Studies

Drug Delivery Systems Based on Porous Chitosan/Polyacrylic acid Microspheres

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