“…As a result, the CS-g-PEG/␣-CD complexes have both rod block (PEG-␣-CD inclusion) and coil block (ionized CS backbone). Jenekhe et al and Jiang et al have reported that the rod-like block in rod-coil system preferred parallel packing crowdedly and resulted in the formation of hollow spheres for necessary of the efficient spacefilling packing (Chen & Jiang, 2005;Duan & Chen, 2001;Duan et al, 2004;Harada et al, 1993;Huang et al, 1998;Jenekhe & Chen, 1998; Jenekhe & Chen, 1999;Kuang et al, 2003Kuang et al, , 2004 With the formation of insoluble PEG-␣-CD inclusion blocks, water became a selective solvent for the CS-g-PEG/␣-CD, so hollow spheres were formed. The expected structure of such an aggregate in aqueous solution is an inner PEG-␣-CD inclusion block surrounded by the protonated coil-like CS shell.…”