Study of the factors associated with recurrence in children with sacrococcygeal teratoma

Type 2 sacrococcygeal teratoma endodermal sinus tumor

“…1 The majority of patients have type 1 or 2 SCTFapproximately 36% of cases are type 1, 27% type 2, 18% type 3 and 18% type 4 (ref. 6).…”

“…6 The risk of recurrence is approximately 10% for benign, mature SCT. However, some benign SCT cases unfortunately have recurred with malignant elements.…”

Sacrococcygeal Teratoma

“…Derikx et al [38] and De Backer et al [39] studied the factors responsible for tumor recurrence in a cohort of 173 and 70 children respectively. Incomplete excision [38], failure to excise coccyx [39] and malignant or immature histology have emerged as risk factors of tumor recurrence [38,39]. Microscopic residue of mature or immature teratoma at the resection margin was rarely associated with local recurrences; however, presence of yolk sac tumor (YST) component was an exception to this rule [39].…”

“…Incomplete excision [38], failure to excise coccyx [39] and malignant or immature histology have emerged as risk factors of tumor recurrence [38,39]. Microscopic residue of mature or immature teratoma at the resection margin was rarely associated with local recurrences; however, presence of yolk sac tumor (YST) component was an exception to this rule [39]. In case of cystic teratomas spillage of solid components rather than the cyst fluid was responsible for recurrences [39].…”

“…Microscopic residue of mature or immature teratoma at the resection margin was rarely associated with local recurrences; however, presence of yolk sac tumor (YST) component was an exception to this rule [39]. In case of cystic teratomas spillage of solid components rather than the cyst fluid was responsible for recurrences [39]. According to Derikx et al [38] tumor size, Altman type and age at diagnosis are not associated with recurrence.…”