Study of the effects of concomitant elements in inductively coupled plasmamass spectrometry

Precise Determination of Trace Elements in Geological Samples by ICP-MS Using Compromise Conditions and Fine Matrix-Matching Strategy

“…In ICP-MS analysis, a large excess (≥1000 µg ml -1 ) of one single element can cause suppression or enhancement of analyte signals; these effects are most extreme with heavy mass elements such as uranium and may be also with light mass elements such as sodium. 12 Fortunately, such matrix effects are not usually a problem in geological samples since any one single element does not generally occur at a high concentration in these samples. In general, non-spectroscopic matrix effects in ICP-MS analysis are best overcome by using more diluted solutions.…”

Liver Biopsy

“…Nebulization and transport processes can be affected if a matrix component causes a change in surface tension or viscosity. Changes in matrix composition can cause significant signal suppression or enhancement (Beauchemin et al, 1987). Dissolved solids can deposit on the nebulizer tip of a pneumatic nebulizer and on the interface skimmers (reducing the orifice size and the instrument performance).…”

Inductively coupled plasma mass spectrometry for stable isotope metabolic tracer studies of living systems

“…This interference is known as matrix-induced signal suppression [101-1151. In some cases, matrix induced analyte signal enhancement is also observed [116]. ICP mass spectrometrists have come a long way in studying and understanding matrix effects [117].…”