Silicates, glasses, and oxides are widely used in everyday applications such as surfaces of cell phones and tablets as well as in nanostructured form for therapeutics, catalysts, and composites. Modeling of the inorganic-organic interfaces at the 1 to 100 nm scale has recently become more viable as suitable force fields and molecular models including details of oxide surface chemistry and pH dependent ionization have been introduced. Here we describe computational models for glasses, silica, and common oxides for simulations at high temperatures and at room temperature, including necessary chemical specificity to analyze surfaces and organic interfaces. The bulk structure of glasses, surface chemistry and type of molecular interactions governing adsorption, as well as the feasible accuracy is illustrated by examples. Applications and opportunities of simulation methods are discussed.