Study of the adjuvant properties of beta-glucans from <i>Saccharomyces Cerevisiae</i> yeast
Ekaterina A. Volosnikova,
D. N. Shcherbakov,
N. V. Volkova
et al.
Abstract:To increase the effectiveness and immunogenicity of modern vaccines, especially subunit ones, it is required to use adjuvants. Polysaccharides, due to their safety and biocompatibility, are desirable candidates for the creation of vaccine adjuvants. The aim of our study was to develop a method for obtaining beta-Glucans from the yeast Saccharomyces cerevisiae cell wall, and evaluate their adjuvant properties. The high purity and non-toxicity of the resulting preparation was achieved by using enzyme complexes o… Show more
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