Study of the accelerated stability of natural repellents against mosquito bites that transmit endemic diseases

Abstract

The Aedesaegypti mosquito is the vector that transmits several diseases, such as dengue, yellow fever, zika virus, and chikungunya fever. The most used control of the spread of the Aedes aegypti mosquito today is chemical insecticides. However, over time, this mosquito created resistance in response to insecticides, requiring new alternatives capable of inactivating it without harming humans and the environment. In this sense, essential oils extracted from aromatic plants are widely used in the cosmetic and pharmaceutical industries due to their availability in the Brazilian flora. They have great potential to replace chemical insecticides. This project aims to produce a repellent cream by adding glycolic extract of monkey pepper (Piper aduncum) and clove (Syzygium aromaticum.) The emulsion will be prepared in two phases, the hydrophilic and the lipophilic phase; the quality control of the cream will be carried out based on accelerated stability in terms of the parameter’s centrifugation, freezing and thawing cycles, density, spreadability, organoleptic characterization, stability at extreme temperatures and pH.