Background: Development of newer techniques of surgical wound closure which are not associated with contamination. Aim is to evaluate advantages and disadvantages of skin closure with sutures and staples. Methods: A controlled experimental study was conducted on guinea pigs divided into two groups of 10 each in NIMS Medical College, Jaipur, in the year 2013. On 5 th POD signs of inflammation (redness, oedema), discharge (serous/seropurulent/purulent), dehiscence (partial or complete) was assessed. On 15 th POD sutures and staples were removed and a strip of scar tissue excised for measurement of tensile strength and histopathology of each wound. Results: Average time taken to close a wound in group 'A' 92.8 sec and in group 'B' 30.3 sec, in group 'A' two showed redness, one swelling & one serous discharge, in group 'B' one redness, two swelling and one serous discharge, tensile strength in group 'A' was 429.9 grams and in group 'B' 393.6 grams., average cost per wound closure was negligible in group 'A' whereas in group 'B' it was Rs. 160/-. There is paucity of literature correlating tensile strength of the healed wound in relation to histopathology of scar tissue. The results were very encouraging, that in group 'A' fibroblastic proliferation and collagination was +++, in group 'B' it was ++ & + respectively. Conclusions: Wound closure with staples is almost three times faster thus time saving but less tensile strength of scar tissue than with sutures. Kochar MP et al. Int Surg J. 2015 Aug;2(3):369-372 International Surgery Journal | July-September 2015 | Vol 2 | Issue 3 Page 370 A single longitudinal skin incision deep till deep fascia was created. Each wound was closed with plain interrupted silk sutures in group 'A' and with staples in group 'B' after achieving haemostasis. All wounds were closed by a single operator to get uniform results. Time taken for skin approximation was measured by an independent observer, wounds after cleaning with povidone-iodine lotion dry gauge dressing applied and covered with adhesive plaster to avoid damage to dressing by self or by other animals. Animals were kept in group of five in different cages. On 5 th POD signs of inflammation (redness, oedema), discharge (serous, seropurulent, purulent), dehiscence (partial, complete) was assessed.
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On 15th POD again after anaesthetising the guinea pigs sutures and staples removed, wound length measured and a strip of scar tissue excised from each wound and tensile strength measured by tensilometer. Wound thus created was again closed, dressed and guinea pigs returned to their cages. A block of scar tissue send for histopathology to see -fibroblast with their maturity stages, fibrocytes and their intermediate stages, neovascularisation, collagination, inflammatory cell type and quantity, inflammatory oedema, epithelialisation, gram's staining for bacterias etc.Kochar MP et al. Int Surg J. 2015 Aug;2(3):369-372 International Surgery Journal | July-September 2015 | Vol 2 | Issue 3 Page 371
DISCUSSIONGuinea p...