Study of skin aging effects induced by near UV radiation using time average digital holographic interferometry

Acosta, José Luis Silva; Santoyo, Fernando Mendoza; Moreno, Jorge Mauricio Flores; Montes, María del Socorro Hernández; Torre-Ibarra, Manuel De la; R, Gloria Frausto; S, Silvino Muñoz; Hernández, Edgard Efrén Lozada

doi:10.1016/j.optlaseng.2020.106345

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…Melanin pigments, which are synthesized in melanocytes and transported to keratinocytes via a complex biological process, are responsible for skin pigmentation. 2,3 Long-term skin exposure to UV radiation as an effective environmental factor causes internal and external damage to the outer skin layers, resulting in skin aging and serious disorders including cancer, 4 which is a critical public health issue in many areas with high solar irradiation. Initial reactions including inflammation and erythema, as well as delayed reactions like photo-carcinogenesis and photo-aging, are the most common consequences of UV irradiation on normal skin.…”

Section: Introductionmentioning

confidence: 99%

“…Flavonoids have attracted a lot of interest as potential natural antioxidant agents for use in skin care products because of their low toxicity, high antioxidant activity, and ability to scavenge reactive oxygen species (ROS). 6,7 Morin (3,5,7,20,40-pentahydroxyflavone) (Figure 1), a flavonol family member, is widely distributed in plants, with onion, morus, and seaweed being particularly abundant. 8 It is characterized by its antiinflammatory, 9 anticancer, 10 antityrosinase, 11 and antioxidant 12,13 activities.…”

Section: Introductionmentioning

confidence: 99%

“…Changes in skin strength, elasticity, and pigmentation are clinical aspects of skin aging. Melanin pigments, which are synthesized in melanocytes and transported to keratinocytes via a complex biological process, are responsible for skin pigmentation 2,3 . Long‐term skin exposure to UV radiation as an effective environmental factor causes internal and external damage to the outer skin layers, resulting in skin aging and serious disorders including cancer, 4 which is a critical public health issue in many areas with high solar irradiation.…”

Section: Introductionmentioning

confidence: 99%

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Characteristics and in vitro anti skin aging activity and UV radiation protection of morin loaded in niosomes

Mohamadi

Soltanian

Raeiszadeh

et al. 2022

J of Cosmetic Dermatology

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Background: One of the dermatologic problems in elderly people is skin aging, which is a natural and complex biological process. Morin is a flavonoid with high radical scavenging activity as well as antityrosinase effects but its low water solubility has restricted its application.Aims: This research aimed to develop, characterize, and optimize morin niosomes composed of non-ionic surfactants, and evaluate the in vitro UV protection and antiaging effectiveness.Methods: Niosomes were prepared by the film hydration method with sorbitan monostearate (Span® 40), polyoxyethylenesorbitan monopalmitate (Tween® 40), and cholesterol. The niosomes were characterized in terms of size, zeta potential, morphology, in vitro release behavior, and drug entrapment efficiency (EE). Afterward, antiaging activity, including antityrosinase, antioxidant, intracellular reactive oxygen species (ROS) scavenging, and sun protection factor (SPF) were evaluated. Results:The optimized niosomes appeared as unilamellar vesicles with a spherical shape, with size, zeta potential, and EE values of 6.13 ± 0.40 μm, −0.81 ± 0.32 mV, and 89.35% ± 2.80%, respectively. The noisome formulation remained stable at −4°C for 3 months. The release profiles of morin loaded in niosomes revealed the extended release over 8 h and followed zero-order release kinetics. Morin-loaded niosomes exhibited no significant toxicity toward the L929 cell line. The niosome loaded with morin showed anti skin aging activity, including antityrosinase effects (IC50 = 13.17 ± 1.58 μg/ml), antioxidant (IC50 = 28.49 ± 2.05 μg/ml), and ROS scavenging activity. For 1% and 5% (w/w) morin niosomes in eucerin base cream, the SPF was 39.03 ± 1.01 and 38.15 ± 0.82, respectively, whereas the noisome-free morin cream exhibited an SPF of 4.47 ± 0.56. Conclusion:Morin-loaded niosome has been shown to provide sun protection and antiaging effects, suggesting that it could be used in pharmaceutical and cosmetic products.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Characteristics and in vitro anti skin aging activity and UV radiation protection of morin loaded in niosomes

Mohamadi

Soltanian

Raeiszadeh

et al. 2022

J of Cosmetic Dermatology

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Impact of the preservation media on ex vivo bone samples for full field mechanical testing

Guzman V.,

De La Torre I.,

Frausto-Reyes

2024

Appl. Opt.

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The preservation method to store bone tissue for posterior analysis is a widespread practice. However, the method’s potential influence on the material’s mechanical properties is often overlooked during single-point experimentation. Saline and formaldehyde solutions are the most common among the employed preservation media. A full field analysis of the mice femoral bone deformation using non-destructive optical techniques is conducted to assess the influence of the storage media on the viscoelastic properties of the tissue. Three different groups are subjected to a standard three-point bending test. The first group is the control, with fresh post-mortem samples. The second and third groups used saline and formaldehyde solutions, respectively. During the mechanical test, the bone’s surface and internal deformation are monitored simultaneously using digital holographic interferometry and Fourier-domain optical coherence tomography. A mechanical comparison among the three groups is presented. The results show that after 48 h of immersion in saline solution, the mice bones keep their viscoelastic behavior similar to fresh bones. Meanwhile, 48 h in formaldehyde modifies the response and affects the marrow structure. The high sensitivity of the optical phase also makes it possible to observe changes in the anisotropy of the samples. As a comparison, Raman spectroscopy analyzes the three bone groups to prove that the preservation media does not affect a single-point inspection.

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New Formulation of TiO<sub>2</sub>- ZnO Slurry for Facial Foundation Sunscreen Cream Application

Pijarn

Jankasemsook

Suwantha

et al. 2021

MSF

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The objective of this research was to prepare ready-to-use TiO2 and ZnO in slurry form for ready-to-use in facial foundation sunscreen. Two types of TiO2 sources were prepared as TiO2 slurry namely commercial TiO2 powder and synthesized TiO2 powder. Preparation of formula 1, 35 g solution PEG-10 dimethicone, and added 20 g solution cyclomethicone after that 45 g TiO2 powder was added slowly to the prepared substance, stirring and heated to 60-70 °C, and stir until the substance mix well. Formula 2, 46 g solution cyclomethicone added 2.5 g stearic acid and 2 g aluminum hydroxide after that stirring and heated to 60-70 °C until the substance mixed well, and TiO2 powder 49.5 g was added slowly to the continuous stirred and heated. On the other hand, ZnO slurry was prepared in the same steps. The results show that formula 1was the best formulation. Due to it was not precipitation and good compatibility with an emulsifier, therefore, formula 1was chosen to study in various volumes. The texture and stability of the prepared slurry were similar to the commercial slurry. Two sunscreen formulas were differently formulated by containing prepared and commercial slurry and evaluated. There were no significant differences in results between prepared slurry and commercial slurry. To investigate the satisfaction of products, 30 volunteers were asked to use products for one week and answer the questionnaires. The product containing prepared slurry was satisfied by 93.33% of volunteers, whereas the product containing commercial slurry was satisfied by 76.66% of volunteers.

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Study of skin aging effects induced by near UV radiation using time average digital holographic interferometry

Cited by 4 publications

References 20 publications

Characteristics and in vitro anti skin aging activity and UV radiation protection of morin loaded in niosomes

Characteristics and in vitro anti skin aging activity and UV radiation protection of morin loaded in niosomes

Impact of the preservation media on ex vivo bone samples for full field mechanical testing

New Formulation of TiO<sub>2</sub>- ZnO Slurry for Facial Foundation Sunscreen Cream Application

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