Study of Prevalence Presentation and Outcome of Plasma Leakagein Dengue Fever Patients Attending Private Medical Clinic inAden - Yemen

Abstract

Background: Dengue virus infections are a significant threat to human populations particularly in the tropical and subtropical regions. Aedes aegypti mosquito from humans to humans mainly transmits this. The main pathological mechanisms associated include thrombocytopenia and plasma leakage. Aim of Study: This study aimed to describe the prevalence presentation and outcome of plasma leakage in dengue fever patients attended a private clinic in Aden-Yemen. Patients and Methods: A retrospective study included 50 patients with dengue fever presented with fever and confirmed with positive dengue NS 1 antigen in the blood in the period from May to October 2020; all patients had done abdomen sonogram for plasma leakage features gall bladder wallo edema, ascites and pleural effusion. Results: 50 patients were recruited in this study, male constitute (60%) female (40%), (58%) of patients came from urban areas, while (42%) came from rural areas, (40%) of patients had plasma leakage manifestation seen by sonogram, (75%) of those patients with plasma leakage were female, (25%) were male, Thick gall bladder is the most common finding in sonogram (70%) reflecting plasma leakage, Overall mortality was (2%) in the enrolled patients in this study. Conclusion: Prevalence presentation and outcome of plasma leakage among dengue fever Yemeni patients do not remarkably differ from studies carried out worldwide.