Study of prevalence and pattern of dyslipidaemia in type 2 diabetes mellitus patients attending rural health training centre of medical college in Bhopal, Madhya Pradesh, India

Abstract

INTRODUCTIONDiabetes mellitus (DM) has become major public health problem in India. It is a metabolic disorder caused by impaired insulin secretion, peripheral insulin resistance or both. It is characterised by raised blood glucose with diminished uptake and metabolism of cellular glucose as well as altered lipid and protein metabolism.1 Diabetes is not only increasing morbidity and mortality but also decreases the quality of life. Also disease and its complications are causing heavy economic burden for patients suffering from it. 2,3ABSTRACT Background: Diabetes is endemic globally with increasing prevalence in both developing and developed countries. Persistent hyperglycaemia of diabetes is associated with micro as well as macro vascular complications like coronary heart disease, stroke, diabetic renal disease, diabetic retinopathy and neuropathy etc. Dyslipidemia contribute to considerable increased risk of atherosclerosis and consequent mortality in diabetic patients. It often precedes onset of diabetes particularly type 2 DM and may persist inspite of adequate control of blood sugar. The objective of the study was to study prevalence and pattern of dyslipidemia in type 2 diabetes mellitus patients attending Rural Health and Training Centre of medical college in Bhopal, Madhya Pradesh. Methods: This was a cross sectional study carried out among 50 Type 2 diabetic mellitus patients attending OPD of Rural Health Training Centre (RHTC) of medical college in Bhopal Madhya Pradesh. Study population included known as well as newly diagnosed type 2 diabetic patients more than 30 years of age attending OPD at RHTC. Results: According to ATP III guidelines dyslipidemia was observed in 43 (86%) study subjects. Hypercholesterolemia was seen in 18 (36%) study subjects. Increased LDL and triglycerides was observed in 33 (66%) and 32 (64%) study subjects respectively. Lower HDL cholesterol values were observed in 26 (52%) study subjects. Out of 43 study subjects having dyslipidemia, 14 (32.6%) study subjects were having isolated single parameter dyslipidemia, while 10 (23.2%) had combined two parameter dyslipidemia and 19 (44.2%) study subjects showed mixed dyslipidemia. Conclusion: Results suggest high (86%) prevalence of dyslipidemia among type 2 diabetes mellitus study subjects. Most common pattern observed was mixed type dyslipidemia. These lipid abnormalities might be the important in view of development of cardiovascular or cerebrovascular diseases. Hence type 2 diabetic patient should undergo the routine monitoring of blood sugar and lipid profile so that any abnormalities can be identified and preventive measures along with interventions can be initiated at the earliest.

Prevalence of Dyslipidemia and The Associated Factors Among Type 2 Diabetes Patients in Turbo Sub-County kenya

“…This study found out 86% of the patients with diabetes in the primary care setting had dyslipidemia. This was similar to findings in India where 86% and 89% dyslipidemia prevalence were reported [14,15]. The current study prevalence was lower than findings in Tanzania 95% [16] and Pakistan 94% [17] but higher compared to those done in Nigeria 74% [18].…”

Correlation of blood glucose with lipid profile levels as risks for cardiovascular disease among diabetic patients at Ruhengeri referral hospital

“…The results of the present study show a high prevalence of dyslipidemia in diabetic patients (78.4%). The finding is consistent with Borles et al [21] in India and in agreement with Shrestha and Khanal [22] in Nepal who reported a high prevalence of dyslipidemia (85.3 and 86%), respectively. However, higher prevalence of 95% in Tanzania [23] and 94% in Pakistan [24] was also reported.…”

Dyslipidemia in Patients with Type 2 Diabetes Mellitus in a Tertiary Care Centre: A Descriptive Cross-sectional Study

“…These findings are similar to that of reports from Nepal and elsewhere. 3,13 Atherogenic dyslipidemia was present in most of the patients which might be due to insulin resistance and is exaggerated by the hyperglycemic state and lipotoxicity; all of these factors can lead to increased risk for atherosclerotic cardiovascular disease. 14 Dyslipidemia was more prevalent in patients having higher BMI and high LDL was the most prevalent (93.5%) followed by mixed dyslipidemia (89.7%).…”