Study of poisoning pattern at China Medical University from 1997 to 2007

Zhao, Ming; Ji, Xueying; Wang, N. N.; Liu, S. Y.; Wang, Y. Z.

doi:10.1016/j.puhe.2009.04.010

Cited by 8 publications

(13 citation statements)

References 7 publications

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“…Both intentional and accidental poisonings were common in men and women aged 20–29 years, which is consistent with previous findings in China16 23 and in other countries 26–28. The fact that poisoning is more common among young adults reflects their vulnerability to stress, possibly due to failure or frustration in relationships or exams, maladjustment and inability to cope with the high expectation of parents 29 30.…”

Section: Discussionsupporting

confidence: 92%

“…Pharmaceutical poisoning comprised 32.6% of the various drug poisonings observed in the present study, of which sedatives/hypnotics (28.8%) were the most frequently ingested agents. A similar pattern was also seen in Zhao et al ’s study, although an apparent decline in sedatives/hypnotics poisoning was seen in our study 16. This decline may be connected with the implementation of drug classification control, where patients can only access these drugs with a doctor’s prescription 43.…”

Section: Discussionsupporting

confidence: 90%

“…The widespread use of pesticides, such as organophosphorus compounds, by farmers may increase the risk of poisoning events in this area 15. A previous investigation performed by Zhao et al 16 in this region from 1997 to 2007 showed that (1) medicine was the most common poisoning agent (41.4%), followed by pesticides (15.2%), alcohol (14.1%), carbon monoxide (CO) (12.5%) and food (9.7%); (2) the major medicines were sedatives/hypnotics and the major pesticides were organophosphates; and (3) mortality decreased from 2.1% to 0.4% over the 10-year study period, with an average mortality rate of 1.0%.…”

Section: Introductionmentioning

confidence: 97%

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Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016

Zhang

Wang

et al. 2018

BMJ Open

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ObjectivesUp-to-date information on the patterns of acute poisoning is crucial for the proper management of poisoning events. The objectives of this study were to analyse the characteristics of patients suffering from acute poisoning admitted to the emergency department (ED) in a tertiary medical centre in Northeast China and to compare these characteristics with those of a previous comparable study.DesignRetrospective and descriptive study.SettingData were collected from the hospital information system in Shengjing Hospital, China, from January 2012 to December 2016.ParticipantsAll cases aged ≥11 years old with a diagnosis of acute poisoning.ResultsIn total, 5009 patients aged ≥11 years presented to the ED with acute poisoning during the study period. The average age of the patients was 36.0±15.1 years and over half (52.7%) were in the 20–39age group. The female to male ratio was 1.2:1. Patients with acute poisoning mainly lived in rural areas rather than in urban areas. The majority of patients consumed poison as suicide attempts (56.7%). Men were more commonly poisoned by drug abuse than women, but women outnumbered men in suicidal poisoning. The most common form of poison intake was ingestion (oral intake; 86.2%). The five most common toxic agent groups, in descending order, were therapeutic drugs (32.6%), pesticides (26.9%), alcohol (20.7%), fumes/gases/vapours (11.4%) and chemicals (3.6%). Sedatives/hypnotics in the therapeutic drugs group and paraquat in the pesticides group were the most common toxic agents, respectively. The mortality rate of study participants was 1.3%, with 64 deaths.ConclusionsThe results of this study indicate the need to strengthen education on the rational and safe use of drugs in Shenyang.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 97%

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Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016

Zhang

Wang

et al. 2018

BMJ Open

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“…Regardless of the type of poisoning (intentional or accidental), drug agents were responsible for the second cause of substances involved in poisoning. This finding is consistent with previous studies in different age groups in Iran (13,14,24), and also in other parts of the world (1)(2)(3)(4)(5)(6)(7)(8). The prevalence of drug poisoning in below 12 years of age group was greatly different from Jaraczewska et al 1997 report (36).…”

Section: Age Groupsupporting

confidence: 89%

“…The pattern of poisoning within a country depends on several factors such as the accessibility of various poisons, socio-economic status of the population, religious and cultural influences and drugs prescription manners (1)(2)(3)(4)(5)(6)(7)(8) (Table 1). Different reports of poisoning in Iran indicate that the leading causes of poisoning or chemical injury in Iran are accidental cases followed by drugs poisoning and pesticides exposure, respectively (9-11).…”

Section: Introductionmentioning

confidence: 99%

The Pattern of Poisoning in Southwestern Region of Iran: Envenoming as the Major Cause

Jalali

Savari

Dehdardargahi

et al. 2012

Jundishapur J Nat Pharm Prod

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A B S T R A C TBackground: An analysis performed on the collected data from the Local Drug and Poison Information Centre (DPIC) of Jundishapur University revealed that stings are the main causes of poisonings with frequency of 56%, followed by drug poisoning in 31%, and chemical exposure poisoning in 5.5% in Khuzestan, the southwestern province of Iran. Objectives: The aim of the present study was to report the prevalence of poisoning in Khuzestan province referred to hospitals during the year 2007, on the basis of documents from the local Drug and Poison Information Centre (DPIC) and the main Khuzestan Hospitals Discharge Registry, to elucidate demographic trends of poisoning in this region. Materials and Methods:In the present study, 3258 cases of poisoning including 4.7% of all admissions to hospitals of Khuzestan during one year (2007) were investigated. Antidepressant drugs were the main-drug category inducing poisoning (24.37%). Others include sedative-hypnotics (19%), tricyclic antidepressants (TCA) (14.7%) and cardiovascular drugs (11.4%). Results:The research showed that most poisonings are occurred in autumn (29.6%) season. Besides the high poisoning rate of envenoming by animals in Khuzestan province, it seems that the pattern of poisoning is different with other Iran and worldwide regions. Conclusions: This may raise the attention of health service policy makers in Iran to establish a more effective diagnosis, management and implementing health policy services.

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Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study

Salem,

Abdulrouf,

Thomas

et al. 2024

Journal of Pharmaceutical Policy and Practice

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Introduction Poisoning is a major public health issue and a leading cause of admission to the emergency department (ED). There is a paucity of data describing the epidemiology and cost of acute poisoning. Therefore, this study investigated the epidemiology, patterns, and associated costs of acute poisoning in emergency department of the largest tertiary care healthcare centre in Qatar. Method This study was a retrospective review of the health records of patients admitted to the ED due to poisoning between January 2015 and December 2019. Incidence, clinical characteristics, and costs associated with acute poisoning were assessed. Frequency and percentages were calculated for categorical variables and mean and SD for continuous variables. The relationship between sociodemographic characteristics and poisoning profile was assessed using the chi-square test. A micro-costing approach using the cost of each resource was applied for cost calculations. Result The incidence of acute poisoning was 178 cases per 100,000 patients. Females (56%) and children below 14 years (44.3%) accounted for the largest proportion. Most of the exposures were accidental involving therapeutic agents (64.2%). The mean length of hospital stay was found to be 1.84 ± 0.81 days, and most patients (76.6%) were discharged within the first 8 h. A statistically significant difference was found between age groups and type of toxin (χ2 = 23.3, p < 0.001), cause and route of exposure (χ2 = 42.2, p < 0.001), and length of hospital stay (χ2 = 113.16, p < 0.001). Admission to intensive care units had the highest cost expenditure (USD 326,008), while general wards accounted for the least (USD 57,709). Conclusion Unintentional poisoning by pharmacological agents is common in infants and children. This study will assist in the development of educational and preventive programmes to minimise exposure to toxic agents. Further studies are required to explore the impact of medical toxicology services, and post discharge monitoring of poisoning.

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Study of poisoning pattern at China Medical University from 1997 to 2007

Cited by 8 publications

References 7 publications

Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016

Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016

The Pattern of Poisoning in Southwestern Region of Iran: Envenoming as the Major Cause

Epidemiology, clinical characteristics, and associated cost of acute poisoning: a retrospective study

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