Study of physiological and pathological skin changes in neonates: An east indian perspective

Behera, Binodini; Kavadya, Yatra; Mohanty, Pramod K.; Routray, Dipanweeta; Ghosh, Subhra; Das, Lina

doi:10.4103/ijpd.ijpd_21_17

Cited by 7 publications

(2 citation statements)

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“…The next common dermatosis witnessed was sebaceous gland hyperplasia in 36% of the neonates, which was in agreement with studies by Vijay et al, Balachandran et al, and Behera et al [7,12,13]. However, it was incongruous with studies by Gudurpenu et al and Swathi et al [14,15], in which a 6.8% and 2.8% incidence was found, respectively.…”

Section: Discussionsupporting

confidence: 85%

Spectrum of cutaneous manifestations in neonates at a tertiary care center

Pujitha¹,

Joweriya²,

Ramadevi³

2023

Our Dermatol Online

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Background: The neonatal period encompasses the initial four weeks of extra-uterine life. Skin lesions in neonates range from transient physiological, self-limiting conditions to pathological dermatoses. An awareness of the physiological skin changes in neonates is needed to differentiate them from pathological dermatoses, thereby avoiding unnecessary treatment and mental stress to the parents. Aim: The aim was to study the clinical pattern of neonatal dermatoses and their prevalence at a tertiary care center. Materials and Methods: An institutional, prospective, observational study was conducted at the outpatient department of dermatology, venereology, and leprosy. A total of 195 neonates from the postnatal ward, pediatric ward, and dermatology department of the same institution with at least one cutaneous manifestation over the period of six months were included in the study. Results: Among the 195 neonates, cutaneous manifestations were noted in 176 neonates (90.8%), among which 82 (46%) were males and 94 (54%) were females; 163(92%) were full-term and 14 (8%) were preterm; 89 (51%) were born through vaginal delivery and 87 (49%) by caesarean section. Skin manifestations may be broadly divided into physiological skin lesions accounting for 80% of cases, transient non-infective conditions (10%), eczematous eruptions (2%), birthmarks (3%), and others (5%). The most common among all was the Mongolian spot accounting for 98 (56%) cases. Conclusion: A majority of the neonatal dermatoses were transient physiological, requiring only reassurance and no medical treatment; however proper understanding and identifying the pathological conditions are critical for early diagnosis and intervention. Key words: Neonatal dermatoses; Mongolian spot; Physiological; Sebaceous gland hyperplasia

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Section: Discussionsupporting

confidence: 85%

Spectrum of cutaneous manifestations in neonates at a tertiary care center

Pujitha¹,

Joweriya²,

Ramadevi³

2023

Our Dermatol Online

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“…According to pH-partition theory only the unionized form of the drug can permeate by the lipid barrier in important quantities. Physiological & pathological conditions of skin 15,16 Reservoir effect of horny layer This is present in deeper layer because of irreversible binding of a part that have applied drug with the skin.…”

Section: Ionizationmentioning

confidence: 99%

Transdermal drug delivery system: A review

Choudhary¹,

Singh²

2021

IJPP

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Transdermal Drug Delivery System is controlled medicated that is set on the skin to deliver a particular portion of medicine through the skin and into the circulatory system. It is likewise significant because of its interesting benefit such as less absorption, more uniform plasma levels, improved bioavailability, decrease side effect, efficacy and quality of the product. Transdermal dose structures may give clinicians a chance to offer more therapeutic alternatives to their patients to upgrade their consideration.

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