Study of physico-mechanical and electrical properties of cerium doped hydroxyapatite for biomedical applications

Nisar, Awais; Iqbal, Sajid; Rehman, Muhammad Atiq Ur; Mahmood, Asif; Younas, Muhammad; Hussain, Shahid; Tayyaba, Qanita; Shah, Attaullah

doi:10.1016/j.matchemphys.2023.127511

Cited by 12 publications

(17 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of the impedance spectra reported by Nisar et al [218] demonstrated that the values of the total HA resistance decreased with the Ce doping concentration.…”

Section: Simple and Doped Hydroxyapatite Pelletsmentioning

confidence: 91%

“…Nisar et al [218] reported on the correlation between σ ac and applied frequency (Figure 19). Thus, it was demonstrated that the σ ac values corresponding to Ce-doped HA, with a maximum of 1.7% Ce content, were superior to those corresponding to undoped HA.…”

Section: Ac Conductivity Analysismentioning

confidence: 98%

“…In ceramics, ions are considered network channels of conductive (R) and capacitive (C) sites. In the case of HA, columnar OH − or H + ions could be regarded as conductive sites, whereas immobile ions could serve as capacitive sites [218].…”

Section: Ac Conductivity Analysismentioning

confidence: 99%

“…Relationship between AC conductivity (σac) and frequency for undoped and Ce-doped green hydroxyapatite samples. Reproduced with permission from [218].…”

Section: Ac Conductivity Analysismentioning

confidence: 99%

“…In a comparative study, changes in the real part of ε 1 with frequency were reported (Figure 21) [218]. HA materials [10,[245][246][247].…”

Section: Dielectric Constantmentioning

confidence: 99%

See 4 more Smart Citations

The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films

Duta,

Grumezescu

2024

Materials

View full text Add to dashboard Cite

Recently, the favorable electrical properties of biomaterials have been acknowledged as crucial for various medical applications, including both bone healing and growth processes. This review will specifically concentrate on calcium phosphate (CaP)-based bioceramics, with a notable emphasis on hydroxyapatite (HA), among the diverse range of synthetic biomaterials. HA is currently the subject of extensive research in the medical field, particularly in dentistry and orthopedics. The existing literature encompasses numerous studies exploring the physical–chemical, mechanical, and biological properties of HA-based materials produced in various forms (i.e., powders, pellets, and/or thin films) using various physical and chemical vapor deposition techniques. In comparison, there is a relative scarcity of research on the electrical and dielectric properties of HA, which have been demonstrated to be essential for understanding dipole polarization and surface charge. It is noteworthy that these electrical and dielectric properties also offer valuable insights into the structure and functioning of biological tissues and cells. In this respect, electrical impedance studies on living tissues have been performed to assess the condition of cell membranes and estimate cell shape and size. The need to fill the gap and correlate the physical–chemical, mechanical, and biological characteristics with the electrical and dielectric properties could represent a step forward in providing new avenues for the development of the next-generation of high-performance HA-doped biomaterials for future top medical applications. Therefore, this review focuses on the electrical and dielectric properties of HA-based biomaterials, covering a range from powders and pellets to thin films, with a particular emphasis on the impact of the various dopants used. Therefore, it will be revealed that each dopant possesses unique properties capable of enhancing the overall characteristics of the produced structures. Considering that the electrical and dielectric properties of HA-based biomaterials have not been extensively explored thus far, the aim of this review is to compile and thoroughly discuss the latest research findings in the field, with special attention given to biomedical applications.

show abstract

“…The results of the impedance spectra reported by Nisar et al [218] demonstrated that the values of the total HA resistance decreased with the Ce doping concentration.…”

Section: Simple and Doped Hydroxyapatite Pelletsmentioning

confidence: 91%

Section: Ac Conductivity Analysismentioning

confidence: 98%

Section: Ac Conductivity Analysismentioning

confidence: 99%

“…Relationship between AC conductivity (σac) and frequency for undoped and Ce-doped green hydroxyapatite samples. Reproduced with permission from [218].…”

Section: Ac Conductivity Analysismentioning

confidence: 99%

“…In a comparative study, changes in the real part of ε 1 with frequency were reported (Figure 21) [218]. HA materials [10,[245][246][247].…”

Section: Dielectric Constantmentioning

confidence: 99%

See 3 more Smart Citations

The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films

Duta,

Grumezescu

2024

Materials

View full text Add to dashboard Cite

show abstract

Development of Chitosan/Mg−Zn−HAP/ZrO₂ Bilayer Coating on Ti Alloy for Biomedical Applications

Suganthi,

Avula,

et al. 2024

ChemistrySelect

View full text Add to dashboard Cite

Titanium alloys (Ti−6Al−4V) are being used in many biomedical applications due to their unique properties of bioactivity, excellent mechanical properties, low toxicity, biocompatibility, and long‐term implant application for their satisfactory corrosion resistance. We have developed a new two‐step fabrication process of zirconium oxide (ZrO2) and Chitosan/Mg−Zn−HAP (Chitosan/M−HAP) bilayer layer coating on Ti alloy for biomedical applications. Flower‐structured bilayers were coated by the electrochemical deposition method. Electrochemically deposited bilayer‐coated Ti alloy specimens were characterized by various analytical techniques like field‐emission scanning electron microscope (FE‐SEM), X‐ray diffraction (XRD), and EDS mapping analysis. Furthermore, the developed bilayer (Chitosan/Mg−Zn−HAP/ZrO2) coated Ti alloy samples improved mechanical properties such as adhesion strength (20.1±0.4 MPa) and hardness (446±4 Hv), compared to other coatings. An investigation of polarization curves showed a positive shift in the polarization values (Ecorr, and Icorr) of the Chitosan/M−HAP/ZrO2 bilayer coatings on Ti alloy. Bilayer‐modified Ti alloy samples show good antimicrobial response toward Gram‐negative and Gram‐positive bacteria. Meanwhile, the cell viability and proliferation of the bilayer‐coated samples were evaluated and the exhibited result improved cell proliferation, and bioactivity compared to other coated materials. From the results, it can be evident that the developed Chitosan/Mg−Zn−HAP/ZrO2 bilayer‐coated Ti alloy could be a good potential candidate for biomedical applications.

show abstract

Analysing the impact of Dy dopants on Zn-based hydroxyapatites: modelling and characterization perspectives

BÜYÜK,

BULUT,

TEMUZ

et al. 2024

Bull Mater Sci

View full text Add to dashboard Cite

Study of physico-mechanical and electrical properties of cerium doped hydroxyapatite for biomedical applications

Cited by 12 publications

References 53 publications

The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films

The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films

Development of Chitosan/Mg−Zn−HAP/ZrO₂ Bilayer Coating on Ti Alloy for Biomedical Applications

Analysing the impact of Dy dopants on Zn-based hydroxyapatites: modelling and characterization perspectives

Contact Info

Product

Resources

About

Study of physico-mechanical and electrical properties of cerium doped hydroxyapatite for biomedical applications

Cited by 12 publications

References 53 publications

The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films

The Effect of Doping on the Electrical and Dielectric Properties of Hydroxyapatite for Medical Applications: From Powders to Thin Films

Development of Chitosan/Mg−Zn−HAP/ZrO2 Bilayer Coating on Ti Alloy for Biomedical Applications

Analysing the impact of Dy dopants on Zn-based hydroxyapatites: modelling and characterization perspectives

Contact Info

Product

Resources

About

Development of Chitosan/Mg−Zn−HAP/ZrO₂ Bilayer Coating on Ti Alloy for Biomedical Applications