Study of Nonrandom Chromosome Aberrations in Bone Marrow and Blood Cells of Patients with Non-Hodgkin’s Lymphomas

Abstract

Complete karyotyping of G-stained chromosomes of bone marrow and blood cells was carried out in patients with non-Hodgkin's lymphomas before and after antitumor therapy, in remissions and relapses. Clones with 1q41-43, 2q35, and 6q24-27 deletions were most incident. Their incidence in patients increased after antitumor therapy.