Study of liver cirrhosis over ten consecutive years in Southern China

Abstract

The major etiology of liver cirrhosis in Southern China is viral hepatitis. However, the proportions of viral hepatitis and HBV are gradually decreasing. Alcoholic LC patients exhibit a greater risk of experiencing UGIB, and HBV LC patients may have a greater risk of HCC.

Clinical characteristics and prognostic factors of liver cirrhosis patients with systemic inflammatory response syndrome

“…In another aspect, SIRS is triggered by a “spill over” of inflammatory mediators from hepatocellular destruction. In the present study, SIRS can occur in patients with liver cirrhosis of various etiology, although the HBV‐predominant etiology pattern was consistent with former studies . We found that more patients had mixed etiology in the SIRS group compared with the non‐SIRS patients; in particular, the co‐existence of HBV and alcohol increased the risk of SIRS.…”

Female gender lost protective effect against disease progression in elderly patients with chronic hepatitis B

“…First, the registry might have patient selection bias. But the age and sex distribution of patients in our study is similar to that of a multi-center study of cirrhosis in Southern China17. Second, the cross-sectional study was not an optimal design to prove causality between gender/age and the development of HBV-related cirrhosis.…”

Risk of empyema in patients with chronic liver disease and cirrhosis: A nationwide, population‐based cohort study

“…Chronic liver disease and cirrhosis (CLDC) have been reported as one of the leading causes of death in the world. Viral hepatitis and alcohol abuse are considered as the most common aetiologies of CLDC . CLDC patients are at an increased risk to have various infections resulting liver‐related complications, which may progress to liver failure with a considerable high fatality .…”