Study of lincomycin partition in a recyclable thermo-pH responsive aqueous two-phase system

Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey

“…The extraction rate of flavonoids showed a downward trend with the increase of pH value. The reason for this phenomenon might be attributed to the following aspects ( Wang et al, 2018 , Wang et al, 2021a ): (1) The degree of protonation of the citrate ions varied at different pH values, which would change the extent of interactions (analytes–ATPS components) in the ATPS. When the pH value is greater than 6.0, the polarity of flavonoids increases with the increase of pH, the ability to capture for water molecules is enhanced, and it is easier to enter the hydrophilic lower phase, resulting in a decrease in the extraction rate; (2) The electrostatic interaction between the two phases was influenced by the pH value of the solutions, which resulted in the change in extraction yield values of the flavonoids; (3) The flavonoids were prone to form salts and assumed an anionic state under neutral and alkaline conditions.…”

Double-Stimuli-Responsive (Temperature and pH) Aqueous Biphasic Systems Comprising Ionic Liquids

“…Double-stimuli-responsive systems provide a higher degree of customization of the target application and thus can be more easily adapted to industrial applications. Combining a thermo-sensitive polymer and a pH-sensitive polymer as the phase-forming agents is the most pursued route to develop double-stimuli-responsive ABS. − To the best of our knowledge, the development of IL-based ABS with double responsiveness to temperature and pH was not previously reported.…”