Abstract:Onychomycosis is a long-standing challenging problem. Effective treatment of patients with onychomycosis is a difficult task. Genetically determined resistance of micromycetes to drugs and acquired resistance contribute to problematic treatment. Systemic antimycotic therapy is conducted in case of total or multiple lesions of ungueal plates. The problem of hepatotoxicity of systemic antimycotics is known; however, lesion pattern in patients with onychomycosis and impaired carbohydrate tolerance are sti… Show more
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