Study of head and neck squamous cell carcinoma transcriptome after proton therapy
E. D. Jumaniyazova,
P. A. Vishnyakova,
M. V. Chirkova
et al.
Abstract:Aim. To evaluate changes in the transcriptome of head and neck squamous cell carcinoma (HNSCC) tissue cells in patients after proton therapy.Materials and methods. Biopsy material obtained from 3 HNSCC patients before and after proton therapy at a total dose of 10 isoGy was homogenized, purified, and concentrated. Then total RNA was isolated with further purification and concentration with the RNA Clean & Concentrator kit (Zymo Research). Library quantitation was assessed using the Qubit 2.0 instrument (In… Show more
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