Study of Drug Utilization Pattern during Second Wave of Covid-19 in a Tertiary Care Centre: A Retrospective Cross Sectional Study

Gawali, Ujwala P.; Gurung, Aruna

doi:10.18502/jpc.v10i4.11581

Cited by 2 publications

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“…Vaughn VM et al, suggested that prophylactic-and treatment-dose anticoagulation strategies are associated with lower in-hospital mortality 16 .COVID-19 was associated with inflammation and hypercoagulable states and in some studies elevation of coagulation markers were associated with worse clinical outcomes. Many studies have shown decreased incidence of COVID-19 complications after initiating anticoagulant therapy 17 .…”

Section: Resultsmentioning

confidence: 99%

Untitled

2023

IJPSR

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Background:The WHO declared the coronavirus disease 2019 (COVID-19) outbreak as a global pandemic in March 2020. Since, no specific drugs are currently available for its treatment it is important to document the prescription patterns. Objectives: To evaluate the drug prescribing pattern and assess the disease progression in the patients hospitalized with COVID-19 in a tertiary care hospital. Methods: It is a retrospective study. Using electronic hospital database, we identified 2302 patients between May 2021 to August 2021. Analysis was done using Microsoft Excel 2007. Results: Out of 2302 patients, 1406 (61.1%) were males and 896 (38.9%) were females. Majority were severe 1001 (43.5 %) followed by mild 664 (28.84 %), moderate 555 (24.1%) and asymptomatic 82 (3.56 %). Majority occurred 853 (37.1%) between51-70 years with slight male preponderance 558 (39.69%). Common co-morbidities were hypertension 666 (28.93%) and diabetes mellitus 482 (20.94 %). Total drugs prescribed were 6,123. Average number of drugs per prescription was 2.66. Corticosteroids 1560 (67.77%) and oxygen 1556 (67.59%) were most commonly prescribed. Piperacillin/Tazobactam was the most commonly prescribed antibiotic 1,153 (50.09%). Injectables used were 4,567 (198.4%). Generic drug prescription was 100%. Most drugs 5,515 (90.1%) were prescribed from NLEM, India, 2015. Inpatient mortality was 241 (10.47%), were predominantly male 190 (13.51%) and severe 167 (16.68%). 1896 (82.36%) were discharged and 165 (7.17%) remained hospitalized. Conclusion: Drug utilization for hospitalized patients with COVID-19 complied with the existing guidelines. Men with severe COVID-19 disease are more at risk for worse outcomes and death.

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Section: Resultsmentioning

confidence: 99%

Untitled

2023

IJPSR

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“…COVID-19 is an ongoing pandemic emergency disease; patients were treated according to symptoms and complications. There should not be any criteria for polypharmacy in this pandemic period [13]. The percentage of drugs prescribed from the essential drug list is 83.34%.…”

Section: Malek Et Almentioning

confidence: 99%

“…In disease outcome, deaths were reported in 55.74% of diabetics having COVID-19 compared to 44.26% of non-diabetics having COVID-19. Hence, the mortality rate increases up to 11.48% in diabetics [13].…”

Section: As Shown Inmentioning

confidence: 99%

Prescription Audit and Effects of Comorbidities on Indoor Covid-19 Patients of a Tertiary Care Teaching Hospital

SM,

AR,

et al. 2024

Asian J Pharm Clin Res

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Objective: Management of COVID-19 has been a challenge to the health-care system. The COVID-19 pandemic led to prescribing a greater number of drugs for curing the disease in the initial phase of the pandemic due to a lack of understanding of the pathophysiology of COVID-19, symptomatic treatment was given as no definite treatment was available. This presented an opportunity to assess prescribing practices during the pandemic. Methods: The study presents a retrospective cohort to assess 300 random prescriptions from indoor COVID-19 patients of a tertiary care teaching hospital. The parameters analyzed in the process of the prescription audit were patients’ demographics data, prescribing standards according to the World Health Organization core indicators, clinical diagnosis with the comorbid condition, legibility of handwriting, doctor’s name and signature, and outcome of the disease. Results: Out of 300 cases analyzed, a total of 298 (99.66%) prescriptions were with antimicrobialsa total of 55 (18.3%) patients received antivirals. 167 (55.67%) admitted patients having comorbidities such as hypertension (28%) and diabetes (24.3%). Conclusion: It is observed almost every patient has received antimicrobial in the form of antibiotic or antiviral. About 18.3% of patients received antiviral drugs. The effect of co-morbidity has a significant influence on the outcome of patients having COVID-19, as in this study, mortality rate in diabetic patients is higher up to 11.48% than in non-diabetics.

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Study of Drug Utilization Pattern during Second Wave of Covid-19 in a Tertiary Care Centre: A Retrospective Cross Sectional Study

Cited by 2 publications

References 0 publications

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Prescription Audit and Effects of Comorbidities on Indoor Covid-19 Patients of a Tertiary Care Teaching Hospital

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