Study of discriminant factor M/H ratio in screening for β thalassemia trait
Abstract:Introduction: Beta Thalassemia syndrome is a group of hereditary disorders characterized by genetic deficiency in the synthesis of beta globin chains located on chromosome 11. A major diagnostic challenge is to differentiate between mild microcytic hypochromic anaemia due to BTT from other causes such as iron deficiency (IDA), sideroblastic anaemia etc. The microcytic to hypochromic ratio (M/H ratio) is one of the simplest discriminant functions which is based on the fact that in Iron deficiency anaemia the RB… Show more
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