Study of coronary sinus and its tributaries in pigs

Abstract

Abstract. Introduction:Similarities between the bodies of pigs and humans have encouraged studies in comparative anatomy, trying to describe in detail the anatomical variations that could influence in the xenotransplantation; given that advances in genetics, immunology and biotechnology are large, this possibility is not far. The objective of this work was to make contributions to the vascular study of porcine heart. Methodology: 60 porcine hearts, with an average of five months old and weighing 85-95kg, were obtained from plant Vijagual. After receipt hearts were kept in water for six hours, then they were perfused with polyester resin semi-synthetic and mineral blue color, moreover the left coronary artery was perfused with red mineral color. Subsequently, the hearts were subjected to a process of partial corrosion with potassium hydroxide (15%), then the coronary sinus and its tributary branches were dissected from its origin to its distal segments, path, shapes, sizes, anastomosis and presence of registered anatomical variations. Photographic record of the samples was performed. Results: The origin of the distal caliber of Great cardiac vein (5.36 +/-1,04mm) was determined from the apex at 70% of anatomical pieces studied, and the ventricular groove paraconal in 30% of the pieces analyzed. The arteriovenous trigone was found in 58 of the cardiac structures studied (96.66%). Conclusion: The description of the anatomic variations present in the pig heart structure will contribute to the possibility of xenotransplantation and also provides data for the development of studies on cardiovascular surgery and certain diseases of clinical and epidemiological importance.Keywords: cardiac circulation, comparative anatomy, coronary sinus, heart, venous circulation. Estudio del seno coronario y sus tributarias en cerdos Resumen. Introducción: las similitudes entre el cuerpo del cerdo y el del ser humano han fomentado estudios de anatomía comparada que intentan describir en detalle las variaciones anatómicas que podrían tener influencia en los xenotrasplantes. Teniendo en cuenta que los avances en genética, inmunología y biotecnología son grandes, esta no es una posibilidad lejana. El objetivo de este trabajo era contribuir al estudio vascular del corazón porcino. Metodología: 60 corazones porcinos, con un promedio de cinco meses de edad y un peso de 85-95 kg, se obtuvieron de la planta Vijagual. Después de mantener los corazones recibidos en agua durante seis horas, se sometieron a perfusión con resina de poliéster semisintética y color azul mineral. Además, la arteria coronaria izquierda se perfundió con color rojo mineral. Posteriormente, los corazones se sometieron a un proceso de corrosión parcial con hidróxido de potasio (15%) y, luego, el seno coronario y sus ramas tributarias fueron disecados desde su origen hasta sus segmentos distales, registrando trayectorias, formas, tamaños, anastomosis y presencia de variaciones anatómicas. Se realizó un registro fotográfico de las muestras. Resultados: se determinó que el o...