Abstract:Background: Sickle cell disease is the commonest heritable hematologic abnormality affecting humans and is highly prevalent in central India. Aspartame is the only agent that can prevent sickling tested in-vitro and in-vivo so far. With the available data being relatively scarce, this study aims to study the efficacy of aspartame in sickle cell crisis and sickle cell disease.Methods: Forty cases and controls each were selected as per predefined criteria. Controls were treated with standard therapy of analgesic… Show more
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