Study of Cardiovascular Profile of Women Using Hormonal Contraceptives

Mbakwem, AC

doi:10.4314/nqjhm.v12i1.12313

Cited by 2 publications

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“…Serum HDL-c level in hormonal contraceptive users was decreased by 0.52 mg/dl from non-users. This result was in line with other studies [ 8 , 29 , 30 , 34 ].…”

Section: Discussionsupporting

confidence: 94%

Effects of hormonal contraceptives on lipid profile among women attending family planning unit in Goba Town Public Health Facilities, Bale, Southeast Ethiopia: a comparative cross-sectional study

Turki,

Ayalew,

Mossie

et al. 2023

Reprod Health

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Background Hormonal contraceptives are a widely used contraceptive method for the prevention of pregnancy in women. It is associated with change in lipid profile which results in congestive heart failure, coronary heart disease, angina, deep vein thrombosis and stroke which are the major cause of premature death. We aim to investigate the effects of hormonal contraceptive use on lipid profile among women attending family planning unit in Goba Town Public Health Facilities. Methods A comparative cross-sectional study design was conducted on 93 hormonal contraceptive users and 93 non-users’ women in Goba Town Public Health Facilities from September to November, 2022. Blood samples for the estimation of TC, TG, HDL-c and LDL-c levels were collected. Student's independent t-test was used to compare the results of lipid profiles. One-way ANOVA was used to identify the variation of lipid profile between progestin only pills, DMPA and implant users. Simple linear regression was used to determine the change in lipid profiles in relation to the duration of hormonal contraceptive use. P-value less than 0.05 was considered as statistically significant. Result The mean serum level of TC, TG and LDL-c was significantly increases in hormonal contraceptive users in comparison with non-users. The mean serum level TC, TG, LDL-c and HDL-c was significantly different between DMPA, implanon and POP users. The mean serum level of TC, TG and LDL-c in implanon users was lower than DMPA and POP users. As the duration of DMPA and POP use increases, the serum level of TC, TG and LDL-c were significantly increased. But, the serum level of HDL-c was significantly decreased. LDL-c was significantly increased with the duration of implanon use. Conclusion The mean serum level of TC, TG and LDL-c were significantly increased among hormonal contraceptive users. The mean serum level of lipid profile was significantly different between DMPA, implanon and POP users. The serum level of TC, TG, LDL-c were directly proportional to the duration of DMPA and POP use. Routine evaluation of lipid profiles is advisable before and after initiation of hormonal contraceptives.

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“…Serum HDL-c level in hormonal contraceptive users was decreased by 0.52 mg/dl from non-users. This result was in line with other studies [ 8 , 29 , 30 , 34 ].…”

Section: Discussionsupporting

confidence: 94%

Effects of hormonal contraceptives on lipid profile among women attending family planning unit in Goba Town Public Health Facilities, Bale, Southeast Ethiopia: a comparative cross-sectional study

Turki,

Ayalew,

Mossie

et al. 2023

Reprod Health

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show abstract

“…[3] Data from Nigeria also show increased morbidity from CVD in women. [4] Preeclampsia is one of the leading causes of maternal and neonatal morbidity and mortality affecting 5-8% of all pregnancies in the United States. [5] The prevalence of preeclampsia in developing countries ranges from 1.8% to 16.7%.…”

Section: Introductionmentioning

confidence: 99%

Association of pre-eclampsia with metabolic syndrome and increased risk of cardiovascular disease in women: A systemic review

Udenze

2016

Niger J Clin Pract

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Study of Cardiovascular Profile of Women Using Hormonal Contraceptives

Cited by 2 publications

References 0 publications

Effects of hormonal contraceptives on lipid profile among women attending family planning unit in Goba Town Public Health Facilities, Bale, Southeast Ethiopia: a comparative cross-sectional study

Effects of hormonal contraceptives on lipid profile among women attending family planning unit in Goba Town Public Health Facilities, Bale, Southeast Ethiopia: a comparative cross-sectional study

Association of pre-eclampsia with metabolic syndrome and increased risk of cardiovascular disease in women: A systemic review

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