Study of carcass, organ, muscle, fat tissue weight, and concentration in rats fed CLA or its precursors by principal component analysis

Goonewardene, L. A.; Mir, P. S.; Wang, Z.; Okine, E. K.; Mir, Z.; He, M. L.

doi:10.4141/a03-068

Cited by 4 publications

(1 citation statement)

References 24 publications

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“…This is the first study, to our knowledge, to investigate the effect of supplemental CLA on organ weight and carcass composition in lactating ruminants. In nonlactating laboratory animals, some studies in rats (37) have indicated an increase in internal body organ weight following CLA supplementation, whereas in mice (38,39) and hamsters (17), the increase appears to be mainly in the liver. There is, however, no evidence from the current study that CLA supplementation for 10 wk at doses that caused MFD had any effect on organ weight in lactating ewes.…”

Section: Discussionmentioning

confidence: 94%

A Supplement Containing Trans-10, Cis-12 Conjugated Linoleic Acid Reduces Milk Fat Yield but Does Not Alter Organ Weight or Body Fat Deposition in Lactating Ewes1–3

Sinclair

Weerasinghe

Wilkinson

et al. 2010

The Journal of Nutrition

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Conjugated linoleic acids (CLA) have been demonstrated to be a potent inhibitor of milk fat synthesis in ruminants, but effects on carcass composition and organ weight are unknown. Our objectives in this experiment were to determine the dose response of ruminally protected CLA on the performance, organ weight, and fatty acid (FA) composition of early lactation dairy ewes. Twenty-four multiparous dairy ewes were fed a basal diet for 10 wk that was supplemented with a lipid-encapsulated CLA at 1 of 3 levels: no CLA (control, CON), low CLA (L-CLA), or high CLA (H-CLA) to supply 0, 1.5, or 3.8 g/d, respectively, of both trans-10, cis-12 and cis-9, trans-11 CLA. Dry matter intake was not affected (P > 0.05) by dietary treatment. Ewes fed H-CLA had a 13% higher milk yield compared with those receiving either CON or L-CLA. Compared with CON, milk fat yield (g/d) was 14 and 24% lower in ewes fed L-CLA or H-CLA, respectively. Supplementing ewes with CLA did not affect carcass or organ weights, carcass composition, or organ FA content. Compared with ewes receiving the CON diet, CLA supplementation had little effect on the FA composition of the Longissimus dorsi, although cis-9, trans-11 and trans-10, cis-12 CLA were increased in ewes receiving H-CLA. The current findings are consistent with the view that the energy spared by the CLA reduction in milk fat content was mainly partitioned to milk yield and there was no evidence of organ hypertrophy or liver steatosis.

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Section: Discussionmentioning

confidence: 94%