Study of Bioactivities of Holarrhena pubescence Growing in Bangladesh

Abstract

ABSTRACT:The stem bark of Holarrhena pubescence was tested for anti-diabetic, analgesic, anti-inflammatory and antidiarrheal activities. After 1, 4 and 12 weeks of treatment protocol in alloxan-induced diabetic rats, it showed very negligible reduction of blood glucose level. In 12 weeks treatment protocol H. pubescence demonstrated that, the extract at 300 and 600 mg/kg bw can reduce blood glucose level by 3 and 4 mmol/l, respectively. Bark extract possessed strong analgesic, anti-diarrheal and mild anti-inflammatory activities. A dose of 600-mg/kg showed 69.50% (p<0.05) of writhing inhibition compared to indomethacin (73.76%) for acetic acid-induced analgesic method. In formalin-induced anti-nociception, the extract at 300 and 600 mg/kg bw showed dose dependent antinociception (67.42% and 69.007%, respectively, p < 0.05). The anti-diarrheal study demonstrated significant antidiarrheal potential in a dose dependent manner as demonstrated by reduction of defecation by 64.92% and 71.43%, for 300-and 600-mg/kg bw, respectively.

Sedimentological and petrophysical characterization of the Bokabil Formation in the Surma Basin for CO2 storage capacity estimation

“…Effective storage capacity has been calculated to estimate total volume of CO 2 that can be injected. The reservoir temperature and thermal gradient data (Table 4 ) are collected from 87 . The structural area (Table 4 ) calculated from the top to spill point on a seismic section.…”

A comprehensive review: Holarrhena pubescens

“… They are utilised as an astringent, anthelmintic, febrifuge, stomachic, anti-dysenteric, and anti-diarrheal in the native medical system of Bangladesh [60] .  They are apparently used in other regions of the world to treat diuresis, chronic chest infections, asthma, malaria, vaginitis, diabetes, arthritis, hematuria, epilepsy, bronchitis, diarrhoea, dermatitis, and jaundice [61] , according to reports (Figure 1). [80] Table 11: Pharmacological activities of Holarrhena pubescens No.…”

Trends and prospects of geothermal energy as an alternative source of power: A comprehensive review

“…The Singra well, with over 150 °C bottom hole temperature holds the most auspicious position among the three areas [ 9 ]. Barapukuria coal basin and the Madhyapara hard rock mine area are two other potential zones for geothermal energy, among which the latter was found with a temperature variation in the range of 67°–153 °C, indicating the presence of a low-temperature geothermal reservoir in the area [ 16 ]. Moreover, it is found that the temperature at 2500 m below the earth's surface in the northwestern tip of Bangladesh, near Salbanhat-1 well, was 79 °C and at a depth of 4,000 m it increased to 110 °C [ 17 ].…”

“…However, the subsurface temperature distribution at different depths leads to the feasibility analysis for energy extraction from geothermal resources [ 16 ]. Figure 5 illustrates the subsurface temperature distribution of different areas in southeast regions [ 20 , 21 ].…”