Study of Antioxidant Activity and Immune Stimulating Potency of the Ethnomedicinal Plant, Cassia alata (L.) Roxb

Chatterjee, Saheli; Chatterjee, Sabyasachi; Dey, KK; Dutta, Sikha

doi:10.4172/2167-0412.1000131

Cited by 17 publications

(16 citation statements)

References 33 publications

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“… [ 15 ] DPPH radical scavenging Methanol extract gave IC 50 concentration lower (54 ± 2.20) than BHT standard (72 ± 2.20). [ 42 ] DPPH, Nitric Oxide (NO), Deoxiribose (DOR) Methanol extract: DPPH (% scavenging activity 58.80 ± 2.02), Nitric Oxide (NO) (% scavenging activity 35.01 ± 1.91) and Deoxiribose (DOR) (% scavenging activity 50.52 ± 0.77). [ 11 ] Leaf Antioxidant DPPH radical scavenging Lipid peroxidation Hydroxyl radical DPPH (IC 50 71.35 ± 0.32 μg/ml).…”

Section: Pharmacological Effectmentioning

confidence: 99%

Chemical constituents, usage and pharmacological activity of Cassia alata

Fatmawati

Yuliana

Purnomo

et al. 2020

Heliyon

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Cassia alata or locally known as Ketepeng Cina (Indonesia) and Gelenggang (Malaysia) has been used as a traditional medicine to treat various diseases, especially skin diseases. In addition, C. alata has been reported to have potential anti allergic, anti inflammatory, antioxidant, anticancer, antidiabetic, and antifungal. Metabolite compounds that have been isolated from C. alata include flavones, flavonols, flavonoids glycosides, alatinon, alanonal and β-sitosterol-β-D-glucoside. The compounds have been isolated mainly from the leaves. Further identification is needed to discover the secondary metabolites from other parts of the plant such as seed, flower and bark which are reported to have potent antibacterial and antifungal activity. Therefore, this article highlights the secondary metabolites and biological activity of this plant which has been shown to have pharmacological properties against selected diseases.

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Section: Pharmacological Effectmentioning

confidence: 99%

Chemical constituents, usage and pharmacological activity of Cassia alata

Fatmawati

Yuliana

Purnomo

et al. 2020

Heliyon

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“…C. alata is widely used in folk medicine and home remedies for treating common ailments, such as ring worm, skin diseases, rheumatism, diabetes, stomach pain, constipation and gonorrhoea [3,5]. Numerous past reports on the promising antioxidant effect shown by C. alata extract have prompted the investigation of the influence of drying methods on the antioxidant activity and chemical constituents [6,7,8]. The leaf extract of C. alata is reported to contain phenols, flavonoids and anthraquinones, which is believed to contribute to the strong antioxidant effect of the plant extract [6].…”

Section: Introductionmentioning

confidence: 99%

Characterisation of the Convective Hot-Air Drying and Vacuum Microwave Drying of Cassia alata: Antioxidant Activity, Essential Oil Volatile Composition and Quality Studies

et al. 2019

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The preservation of active constituents in Cassia alata through the removal of moisture is crucial in producing a final product with high antioxidant activity. This study aims to determine the influences of various drying methods and drying conditions on the antioxidant activity, volatiles and phytosterols content of C. alata. The drying methods used were convective drying (CD) at 40 °C, 50 °C and 60 °C; freeze drying; vacuum microwave drying (VMD) at 6, 9 and 12 W/g; and two-stage convective pre-drying followed by vacuum microwave finish drying (CPD-VMFD) at 50 °C and 9 W/g. The drying kinetics of C. alata are best described by the thin-layer model (modified Page model). The highest antioxidant activity, TPC and volatile concentration were achieved with CD at 40 °C. GC–MS analysis identified the presence of 51 volatiles, which were mostly present in all samples but with quantitative variation. The dominant volatiles in fresh C. alata are 2-hexenal (60.28 mg 100 g−1 db), 1-hexanol (18.70 mg 100 g−1 db) and salicylic acid (15.05 mg 100 g−1 db). The concentration of phytosterols in fresh sample was 3647.48 mg 100 g−1 db, and the major phytosterols present in fresh and dried samples were β-sitosterol (1162.24 mg 100 g−1 db). CPD-VMFD was effective in ensuring the preservation of higher phytosterol content in comparison with CD at 50 °C. The final recommendation of a suitable drying method to dehydrate C. alata leaves is CD at 40 °C.

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“…Among the antioxidants, polyphenol derivatives such as phenolic, flavonoid, and flavanol contents naturally found in plants are the most beneficial (Salah et al, 1995;Zandi and Gordon, 1995;Kim et al, 2003;Karimi et al, 2011). In addition to those polyphenols, the existences of phytochemical constituents, such as ascorbic acid, tocopherols, and carotenoids in consumable plants enhance their total antioxidant capacity (Chatterjee et al, 2013). Therefore, entire leaves either raw, cooked or processed into beverages are commonly consumed.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of antioxidant capacity of Aidia borneensis leaf infusion, an endemic plant in Brunei Darussalam

Metussin¹,

Mohamed²,

Ahmad³

et al. 2017

Food Res.

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We investigated the total antioxidant capacity of Aidia borneensis leaf infusion, a Bornean endemic plant, which is traditionally consumed as a home-remedy beverage in Brunei Darussalam. The antioxidant capacity of the infusion of A. borneensis leaves was evaluated by 2,2-diphenyl-1-picryhydrazyl (DPPH) radical-scavenging ability. We found that the infusion shows a relatively high antioxidant capacity, and it was attributed to its high phenolic, flavonoid, and flavanol contents which were evaluated by Folin-Ciocalteu reagent, colorimetric assay, and aluminum chloride colorimetric method, respectively. By comparing its total antioxidant capacity, we estimated that the infusion of A. borneensis leaves is in the middle rank among twelve different commercially available Camellia sinensis teas. Our findings would have significant implications on A. borneensis products from Brunei Darussalam and on the feasibility of establishing this new beverage among the commercially available conventional C. sinensis and herbal teas.

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Study of Antioxidant Activity and Immune Stimulating Potency of the Ethnomedicinal Plant, Cassia alata (L.) Roxb

Cited by 17 publications

References 33 publications

Chemical constituents, usage and pharmacological activity of Cassia alata

Chemical constituents, usage and pharmacological activity of Cassia alata

Characterisation of the Convective Hot-Air Drying and Vacuum Microwave Drying of Cassia alata: Antioxidant Activity, Essential Oil Volatile Composition and Quality Studies

Evaluation of antioxidant capacity of Aidia borneensis leaf infusion, an endemic plant in Brunei Darussalam

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