Study of angiographic association of atherosclerotic renal artery stenosis with coronary artery disease in Bangladesh

Abstract

This retrospective observational study aimed to see the angiographic association of atherosclerotic renal-artery stenosis (ARAS) with coronary artery disease in Bangladesh. It was conducted in department of cardiology, University Cardiac Centre, Bangabandhu Sheikh Mujib Medical University, Dhaka from January 2007 to January 2008. A total of 250 patients with coronary artery involvement, on non-emergent coronary angiogram who underwent either selective or nonselective renal angiography were enrolled in this study. Among 250 patients, 52 (20.8%) patient had single vessel disease (SVD), 49 (19.6%) and 149 (59.6%) had double vessel disease (DVD) and triple vessel disease (TVD) respectively. ARAS was detected in 37.2% or 93 patients. ARAS tends to increase with age. In age group of 30-40, ARAS is 7.4% whereas in age group of 51-60 years it is 41%. The incidence of ARAS is high in 50.25±9.98years; p=0.0001. 33.3% male patients with CAD had ARAS whereas it was 44.3% in female patients with CAD. ARAS is more common in female 44.3% vs 33.3%; p=0.02. ARAS prevalence increased with the number of stenosed coronary arteries (3.8% in 1-vessel, 26.5% in 2-vessel, 52.3%in 3-vessel CAD; p=.0001.). Hypertension and angiographically proven CAD were independent predictors of ARAS (p=0.0001). In conclusion, ARAS prevalence and severity increases with the number of arterial territories involved and CAD severity. Hypertension and 2-3-vessel-CAD were identified independent predictors of ARAS.  doi:10.3329/uhj.v4i2.2069 University Heart Journal Vol. 4 No. 2 July 2008 p24-27

Renal Artery Stenosis and Its Predictors in Hypertensive Patients Undergoing Coronary Artery Angiography

“…The association between old age and RAS in our study was similar to that described in other researches and more studies have shown that patients with significant RAS are older [22][23][24]. Here, there is a strong and independent relation between old age and RAS which shows a later or slower start of atherosclerosis in renal arteries rather than the coronary or other peripheral vascular atheroscleroses [25]. Although they met the enrollment criteria, we detected RAS infrequently among individuals less than 60 years of age.…”

Frequency of renal artery stenosis and associated factors in patients undergoing coronary angiography

“…Yet, there is no consensus on the association of gender with RAS; on the other hand, the present study showed no significant difference of gender with RAS, while Sen et al and Olivier et al showed male dominancy (13,17). In contrast, Islam et al and Cohen et al found female dominancy (16,18). Diabetes mellitus was also significantly associated with RAS in some studies (14,17) and not in some others (15,16) including ours.…”