Study of an association between SNP 775C>T within the bovine ITBG2 gene and milk performance traits in Black and White cows

Abstract

ABSTRACT:The exclusive pre-selective effect of BLAD carriers reproducing in the exposed Holstein-Friesian cattle population prompted to search for the candidate gene variants of high quality of milk performance traits within the bovine ITBG2 gene or loci linked with bovine ITBG2 gene. Theoretical considerations indicated that the "silent mutation" C→T localized at the position of 775 bp of the gene encoding the CD18 subunit might be a potential QTL marker of high milk productivity. An association study between the polymorphism of SNP 775C>T, and the diversification of milk performance traits was carried out on the progeny of four bulls with genotypes BL/TL and 775C/T and one bull with genotypes TL/TL and 775C/T. The results documented statistically significant differences in the protein content percentage of milk in two half-sib families of bulls with BL/TL and 775C/T genotype and one half-sib family of bull with TL/TL and 775C/T genotype. It was further concluded that the polymorphism of SNP 775C>T was found to be a more efficient QTL marker than that of D128G, since in all the analysed milk performance traits for half-sib families higher values of the F coefficient were obtained for the SNP 775C>T mutation in comparison with D128G.

The association between microsatellite Bm6438 and milk performance traits in Polish Holstein-Friesian cattle

“…The results of variability of milk performance evaluation were compiled taking into account differences in milk yield as well as in fat and protein contents of milk in cows kept in different herds (Czarnik et al, 2007). The relationship between the genetic polymorphism of the marker BM6438 and the variation in milk performance traits within each of the three families was analyzed by the following linear models using the ANOVA procedures (Statistica 9, Statsoft Inc).…”

Excited State Properties and Energy Transfer within Dipyrrin‐Based Binuclear Iridium/Platinum Dyads: The Effect of ortho‐Methylation on the Spacer

“…Laboratory techniques and mathematical and statistical methods for the evaluation of animal breeding values (BV) are undergoing continuous improvement. Molecular genetic data can be analysed for associations with production traits 1. However, the relationships between farm animal production traits and molecular‐genetic information are often measured imprecisely.…”