Study of a case of an ovarian cyst that redeveloped after treatment for anti-NMDA receptor encephalitis

Abstract

Objectives: The objectives of this study were to discuss the disease state and recent topics related to the redevelopment of an ovarian cyst after the treatment of anti-N-methyl-D-aspartate (NMDA) receptor encephalitis. Herein, we present a case report with its postoperative course, and describe the problems in patients who redevelop ovarian cyst with no symptoms of encephalitis.Case: The subject developed anti-NMDA receptor encephalitis, for which abdominal surgery for bilateral resection of an ovarian cyst was performed. While the patient was discharged from the hospital 3 months post-surgery, after the encephalitis symptoms had improved, the ovarian cyst subsequently redeveloped, and thus laparoscopic resection of the ovarian cyst on the affected side was performed in our hospital. Redevelopment of an ovarian cyst was confirmed again on the same side 2 years after the surgery performed in our hospital. Conclusion:Although redevelopment of encephalitis has been reported in patients with anti-NMDA receptor encephalitis, no therapeutic methods have been established for the redeveloped ovarian cyst in the absence of encephalitis symptoms.Since its pathological conditions have become more widely recognized, it is expected that more cases will accumulate, thus allowing further discussion and the establishment of therapeutic policies for the redeveloped ovarian cyst.