Studies with polyfunctionally substituted heteroaromatics: synthesis of several new thiazoles, pyrazolo[5,1-c]triazines and of polyfunctionally substituted pyridines and pyrimidines.

Catalytic performance of nanostructured iron oxides synthesized by thermal decomposition technique

“…3b shows that the samples F12 and F13 have a strong peaks at 2086, 2079 cm −1 corresponding to CN group [32], and broad peak at 3398-3381 cm −1 and sharp peak at 1626 cm −1 are also detected corresponding, respectively to the stretching vibration of -OH and -O(OH) groups on the surface [29]. This result is in a good agreement with XRD data which confirmed that iron cyanide hydrated is formed.…”

Six‐Membered Heterocycles: Triazines, Tetrazines and Other Polyaza Systems

“…Compounds that provide the C(3) include aldehydes [271][272][273][274], isothiocyanates [275], nitriles [276], imidates [276,277], thioimidates [276], ketones, orthoesters [278][279][280][281], carbon disulfide, phosgene, and thiophosgene [282]. Some examples are shown in Scheme 20.51.…”

Synthesis and reactions of pyrazolo[5,1-c][1,2,4]triazine-3-carbothioamides

“…7 According to the patent data, 8 certain polysubstituted pyrazolo [5,1-c] [1,2,4]triazines selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase. The most concise approach to the synthesis of pyrazolo[5,1c] [1,2,4]triazine scaffolds is based on the azo-coupling of pyrazole-3(5)-diazonium salts 1 with active methylene/methine compounds followed by the intramolecular cyclization of hydrazone intermediates 2: 1,9,10 A number of 4-aminopyrazolo [5,1-c] [1,2,4]triazines were obtained by reactions of diazonium salts 1 with methylene active nitriles such as malononitrile [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] , 2-(cyanomethyl)thiazoles, 28,29 2-(cyanomethyl)benzoxazole, 19 ethyl cyanoacetate, 11,17,20,21,26,30,31 α-cyanoketones, 30,[32][33][34][35] 2-(cyanomethyl)thiadiazoles,...…”