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Studies towards the synthesis of radiolabeled R106-1(LY295337)
Abstract: A unique semisynthetic pathway has been used as a route to acquire radiolabeled material of a complex natural product, R106. The retro‐aldol reaction of R106‐1 gave a key intermediate R106‐sarcosine that was used in a subsequent aldol reaction to incorporate acetone‐[2‐14C].
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2001
2001
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