Studies on X Ray Absorption and Diffraction of Bone Tissue

Alizarin as an indicator of bone growth

“…In the interpretation of these features in the microradiographs much care was taken to find areas in which there were no overlapping bone shadows to render the contrast between radio-lucent and radio-opaque bone too difficult. With this reservation, it is probable that the radio-lucent bone is recently formed and poorly calcified (Amprino & Engstr6m, 1952;Amprino, 1953;Vincent, 1955). In animals surviving for longer periods, microradiographs of sections show that the red lines in certain areas have become more radio-opaque.…”

Studies of Bone of Patients With Hyperparathydroidism by Means of Phosphate Exchange Experiments in Vitro and Quantitative Microradiography*

“…Investigations have also been done on bone structures of various ages. The mineral content of young structures is lower than that of older structures (18). In the bone of the human fetus mineralization takes place very rapidly in the first five weeks of this process, but after this period the continued rise in mineral content is very slow (19).…”

Radium in humans: A review of U.S. studies

“…The number of tracks and hence the concentrations of radium varied widely from one microscopic area of bone to another. At about the same time, A. Engstrom in Sweden and R. Amprino in Italy had made microradiographs of thin slices of bone and had shown that the density changes in bone (recorded on the high-resolution X-ray images) clearly detailed the structure of bone on a microscopic scale (Engstrom 1946;Amprino and Engstrom 1952). Marinelli suggested that the two techniques, applied to a single section of bone, might make it possible to understand the metabolism of radium in bone at the histologic level.…”