2003
DOI: 10.1016/j.jep.2003.09.001
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Studies on the toxicity of Punica granatum L. (Punicaceae) whole fruit extracts

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Cited by 177 publications
(123 citation statements)
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“…In addition, it is widely used in therapeutic formula, cosmetics, and food seasonings. Since ancient times, the pomegranate has been regarded as a "healing food" with numerous beneficial effects in several diseases (Vidal et al, 2003). Knowing the importance of health benefits of pomegranate and all related aspects, the present investigation entitled "Comparative evaluation of physico-chemical properties of two varieties of pomogranate fruits-Ganesh and Arakta" was carried out to analyze different physicochemical characteristics of different varieties of pomogranate fruits, that is, Ganesh and Arakta cultivars and to explore these fruits for commercial processing.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, it is widely used in therapeutic formula, cosmetics, and food seasonings. Since ancient times, the pomegranate has been regarded as a "healing food" with numerous beneficial effects in several diseases (Vidal et al, 2003). Knowing the importance of health benefits of pomegranate and all related aspects, the present investigation entitled "Comparative evaluation of physico-chemical properties of two varieties of pomogranate fruits-Ganesh and Arakta" was carried out to analyze different physicochemical characteristics of different varieties of pomogranate fruits, that is, Ganesh and Arakta cultivars and to explore these fruits for commercial processing.…”
Section: Introductionmentioning
confidence: 99%
“…In addition to its ancient historical uses, pomegranate is used in several systems of medicine for a variety of ailments [7][8][9]. The synergistic action of the pomegranate constituents appears to be superior to that of single constituents.…”
Section: Therapeutic Applicationsmentioning
confidence: 99%
“…As falhas na implantação do embrião são uma das principais causas de aborto e podem estar ligadas à exposição materna, interferindo com este evento por diferentes mecanismos que incluem: alterações morfológicas do embrião e fetotoxicidade [31][32][33][34] , alterações dos níveis hormonais [35][36][37][38] e alterações uterinas [39][40][41][42] .…”
Section: Plantas Utilizadas Como Abortivasunclassified
“…Em relação às malformações, o período de pré-implantação em mamíferos é a etapa na qual pode ocorrer letalidade ao embrião ou interferência no desenvolvimento normal do mesmo 31 . No entanto, alguns autores relataram um aumento no número de variações em fetos cujas mães foram expostas aos agentes químicos do vegetal durante este período, bem como atraso no desenvolvimento fetal e morte antes do nascimento 32,33 . Estudos de embriotoxicidade mostram que a administração do extrato da casca da romã (Punica granatum) induz apoptose e fragmentação no DNA em linhagens celulares de humanos 33 .…”
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