Studies on the synthesis of sugar chalcone derivatives for protein binding
Arasappan Hemamalini,
Ayyavu Thirunarayanan,
Subramani Karthikeyan
Abstract:Simple sugar chalcone derivatives are synthesized by the Aldol condensation of various β‐C‐glycosidic ketones with aromatic aldehydes under microwave condition. Zn‐mediated reduction of sugar‐chalcone derivatives results in the formation of the corresponding reduced product. The so obtained products are characterized using NMR (1H, 13C), mass spectroscopy and elemental analysis. The interaction of synthesized sugar chalcone derivatives and their reduced products with Bouvine Serum Albumin studied using computa… Show more
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