Studies on the Placental Transfer in Rats of ⁵⁹Fe‐ and ¹⁴C‐labelled Iron‐poly (sorbitol‐gluconic acid) complex

Abstract

The placental transfer of an iron‐poly (sorbitol‐gluconic acid) complex, Ferastral®, has been studied. By use of the 59Fe‐, 14C‐sorbitol, and 14C‐gluconic acid labelled complexes it was shown that the passage of the iron moiety is related to foetal need and that only negligible amounts of 14C from either 14C‐sorbitol or 14C‐gluconic acid labelled iron complexes were found in the foetus. This implies that the intact complex does not pass the placental barrier.