Studies on the Mayak nuclear workers: health effects

Koshurnikova, N.A.; Gilbert, Ethel S.; Shilnikova, Natalia S.; Sokolnikov, Mikhail; Preston, Dale L.; Kreisheimer, M.; Ron, Elaine; Okatenko, P.V.; Романов, С. А.

doi:10.1007/s00411-001-0130-7

Cited by 24 publications

(7 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies are underway on the workers at this Mayak complex (Koshurnikova 2002), among whom there have been many excess cancers, but exposures were generally quite high and the data reported give little information on the dose-response relationship in the low dose region.…”

Section: Data Contradictory To Lntmentioning

confidence: 99%

Cancer Risk from Low-Level Radiation

Cohen

2002

American Journal of Roentgenology

150

View full text Add to dashboard Cite

Section: Data Contradictory To Lntmentioning

confidence: 99%

Cancer Risk from Low-Level Radiation

Cohen

2002

American Journal of Roentgenology

150

View full text Add to dashboard Cite

“…The Mayak Worker Cohort is a study of nearly 30,000 workers, first employed at the Mayak facility in the years 1948–1982. Detailed descriptions of the Mayak Worker Cohort study population and follow-up methods (12–14) and dose reconstruction methods (15–17) have been previously published. The main plants of the facility consisted of nuclear reactors, a radiochemical plant and a plutonium production plant (16).…”

Section: Methodsmentioning

confidence: 99%

Cancer Mortality FollowingIn UteroExposure Among Offspring of Female Mayak Worker Cohort Members

et al. 2012

Self Cite

View full text Add to dashboard Cite

Little is known about long-term cancer risks following in utero radiation exposure. We evaluated the association between in utero radiation exposure and risk of solid cancer and leukemia mortality among 8,000 offspring, born from 1948–1988, of female workers at the Mayak Nuclear Facility in Ozyorsk, Russia. Mother’s cumulative gamma radiation uterine dose during pregnancy served as a surrogate for fetal dose. We used Poisson regression methods to estimate relative risks (RRs) and 95% confidence intervals (CIs) of solid cancer and leukemia mortality associated with in utero radiation exposure and to quantify excess relative risks (ERRs) as a function of dose. Using currently available dosimetry information, 3,226 (40%) offspring were exposed in utero (mean dose = 54.5 mGy). Based on 75 deaths from solid cancers (28 exposed) and 12 (6 exposed) deaths from leukemia, in utero exposure status was not significantly associated with solid cancer: RR = 0.94, 95% CI 0.58 to 1.49; ERR/Gy = −0.1 (95% CI < −0.1 to 4.1), or leukemia mortality; RR = 1.65, 95% CI 0.52 to 5.27; ERR/Gy = −0.8 (95% CI < −0.8 to 46.9). These initial results provide no evidence that low-dose gamma in utero radiation exposure increases solid cancer or leukemia mortality risk, but the data are not inconsistent with such an increase. As the offspring cohort is relatively young, subsequent analyses based on larger case numbers are expected to provide more precise estimates of adult cancer mortality risk following in utero exposure to ionizing radiation.

show abstract

“…The companion manuscripts in this issue of Radiation and Environmental Biophysics [1,2,3,4,5,6] outline and discuss in detail the ongoing studies of cohorts that have been exposed to ionizing radiation in the former Soviet Union. The establishment of these cohorts was based on (a) the exposure due to the employment in the Mayak Production Association (MPA), i.e.…”

Section: Introductionmentioning

confidence: 99%

“…The establishment of these cohorts was based on (a) the exposure due to the employment in the Mayak Production Association (MPA), i.e. Mayak workers cohort [1], (b) the exposure of the regional Ozyorsk population due to atmospheric releases of radionuclides from MPA, i.e. Ozyorsk population cohort [2], (c) the exposure due to accidental releases from the Mayak facility into the river Techa, resulting in exposed populations, i.e.…”

Section: Introductionmentioning

confidence: 99%

Developing additional resources

Grosche

et al. 2002

Radiat Environ Biophys

Self Cite

View full text Add to dashboard Cite

We briefly outline existing information about several cohorts in the Southern Urals, Semipalatinsk and the Altai regions, in addition to those discussed in the companion papers in this issue of Radiation and Environmental Biophysics. These include: (a) the East-Urals Radiation Trace (EURT) cohort of individuals (exposed to fallout from the September 1957 explosion of a storage tank containing liquid radioactive waste from the Mayak Production Association) as well as their offspring, (b) the cohort of exposed parents (i.e. workers of the Mayak facility) and their children, having been established with the aim of examining reproductive health, and (c) several additional cohorts in the Altai region and in Semipalatinsk, where investment of additional resources would greatly facilitate the progress of ongoing studies. Furthermore, we include a brief description of the Russian Human Radiobiology Tissue Repository, which has been established in the city of Ozyorsk and is in the process of making an inventory of autopsied tissues from 700 deceased Mayak workers and of collecting and storing donations of blood and tumor tissues from the members of the Mayak workers cohort currently residing in the city.

show abstract

Studies on the Mayak nuclear workers: health effects

Cited by 24 publications

References 9 publications

Cancer Risk from Low-Level Radiation

Cancer Risk from Low-Level Radiation

Cancer Mortality FollowingIn UteroExposure Among Offspring of Female Mayak Worker Cohort Members

Developing additional resources

Contact Info

Product

Resources

About