Studies on the mass receptor potential of the isolated frog retina

Sillman, Arnold J.; Ito, Hiroshi; Tomita, Tsuneo

doi:10.1016/0042-6989(69)90059-5

Cited by 238 publications

(95 citation statements)

References 13 publications

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“…Ion substitution experiments suggest that these effects are mainly due to a decrease in membrane permeability to sodium (Sillman, Ito & Tomita, 1969;Arden & Ernst, 1970;Cervetto, 1973). A light-induced increase in input resistance has been described also in rod cells of the gecko (Toyoda et al 1969).…”

Section: Introductionmentioning

confidence: 98%

Light‐induced resistance changes in retinal rods and cones of the tiger Salamander

Lasansky¹,

Marchiafava²

1974

The Journal of Physiology

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3. Values of input resistance were derived from the voltage displacement induced by constant current pulses in darkness or at the peak of the photoresponse. The input resistance following illumination was also calculated from the effect of steady polarizing currents on the amplitude of the photoresponse.4. In darkness, the input resistance of the rod cells is time-and voltagedependent, but the voltage-current relations of most cells have a linear region which includes the physiological limits of membrane potential. At the peak of the photoresponse, the input resistance (slope of the linear region of the v-i relations) is decreased.5. Cone cells show approximately linear v-i relations. As reported by previous authors, illumination increases the input resistance.6. These results support the current view that the cone photoresponse is the consequence of a reduction in the permeability of channels which in darkness shunt the membrane. In rods, however, it appears that the main effect of illumination is to increase the permeability of the membrane to ions for which the equilibrium potential is more negative than the membrane potential in darkness.

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Section: Introductionmentioning

confidence: 98%

Light‐induced resistance changes in retinal rods and cones of the tiger Salamander

Lasansky¹,

Marchiafava²

1974

The Journal of Physiology

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“…To increase the stability and duration of recordings, the perfusion solution was kept at slightly lower temperature, ϳ34°C, than for single-cell recordings. The perfusion Locke solution also contained 2 mM L-glutamate to block the higher order component of the photoresponse (24). The electrode solution under the retina contained, in addition, 10 mM BaCl 2 to suppress the glial component of the transretinal response (25,26).…”

Section: Immunostaining and Estimation Of Relative Cone Grk1 Level Inmentioning

confidence: 99%

Regulation of Mammalian Cone Phototransduction by Recoverin and Rhodopsin Kinase

Sakurai

Chen

Khani

et al. 2015

Journal of Biological Chemistry

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Background: Calcium-mediated feedback to phototransduction is critical for modulating cone responses under different lighting conditions. Results: The calcium-binding protein recoverin potentiates dim light sensitivity, whereas increasing expression of its target, GRK1, delays response shutoff in cones. Conclusion: Recoverin and GRK1 levels modulate cone phototransduction. Significance: Cone pigment inactivation regulates cone responses in dim light but not in bright light.

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“…13,[33][34][35] A test for the contribution of postreceptor, negative ERG components is to examine how background light affects the response to a flash of fixed high intensity, i.e., a flash comparable to the probe flash used in paired-flash experiments. It is known, for example, that the scotopic threshold response (STR) is adapted out, i.e., the flash-generated STR is eliminated, by backgrounds much weaker than those that significantly reduce the rod circulating current.…”

Section: B-wave and Other Postreceptor Componentsmentioning

confidence: 99%