Studies on the male meiosis of &lt;i&gt;Ellobius lutescen&lt;/i&gt;&lt;i&gt;s&lt;/i&gt; Th.

Castro-Sierra, Eduardo; Wolf, U.

doi:10.1159/000129988

Cited by 23 publications

(13 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An association with an autosomal bivalent during male meiosis has been observed in about 25 % of the pachytene figures examined; 75 % of the sex vesicles remained as univalent (Castro-Sierra and Wolf, 1968). From these observations it was concluded that the missing Y chromosome is translocated to an autosome where the single X chromosome forms a pseudo-trivalent with the shared sequences of a putative pseudoautosomal region.…”

mentioning

confidence: 92%

See 1 more Smart Citation

The sex determination in Ellobius lutescens remains bizarre

Just¹,

Baumstark²,

Hameister³

et al. 2002

Cytogenet Genome Res

View full text Add to dashboard Cite

Mammalian sex determination and gonad differentiation are the result of a complex interaction of fine-tuned spatial and temporal gene expression with threshold levels of individual genes. The male pathway is initiated by SRY. Some exceptional mammals determine male sex without the SRY gene and even without a Y chromosome. Ellobius lutescens in this report is one example of this “weird” species. We provide key data on the genomic level that there are no coarse differences in the genomes of male and female animals by comparative genomic hybridization. On the gene level we studied the gene Nr5a1 for the orphan nuclear receptor, steroidogenic factor SF-1, a central constituent for gonad differentiation and adrenal gland development. The Ellobius lutescens Nr5a1 gene was mapped to the proximal short arm of chromosome 2 by fluorescence in situ hybridization. In addition, we provide evidence by linkage analysis in two E. lutescens pedigrees that Nr5a1 is not the key male sex-determining gene in Ellobius lutescens.

show abstract

mentioning

confidence: 92%

“…It was assumed that the testis-determining part of the Y chromosome had been translocated to the X or to one of the autosomes or that the tiny Y chromosome was too small for routine detection by cytogenetic studies (Castro-Sierra and Wolf, 1968). The odd chromosome 9 represents the single X chromosome in the "weird" species Ellobius lutescens.…”

mentioning

confidence: 99%

The sex determination in Ellobius lutescens remains bizarre

Just¹,

Baumstark²,

Hameister³

et al. 2002

Cytogenet Genome Res

View full text Add to dashboard Cite

show abstract

“…Hence, the original hypothesis by Matthey (1953;1958) and White (1957) was refuted and instead a Y autosome translocation proposed to explain the sex chromosome constitution in this species (Castro-Sierra and Wolf, 1967). The latter hypothesis got additional support from an association between the sex vesicle and an autosomal bivalent in a proportion of cells in male meiosis (Castro-Sierra and Wolf, 1968). However, the translocated Y was undetectable by the cytogenetic techniques of that time.…”

mentioning

confidence: 97%

“…3) showed the odd chromosome to be early replicating together with the autosomes in both, males and females. Detailed studies on the male meiosis of Ellobius lutescens suggested also that the odd chromosome represents a standard type, single mammalian X chromosome (Castro-Sierra and Wolf, 1968). Hence, the original hypothesis by Matthey (1953;1958) and White (1957) was refuted and instead a Y autosome translocation proposed to explain the sex chromosome constitution in this species (Castro-Sierra and Wolf, 1967).…”

mentioning

confidence: 99%

Sex determination in Ellobius lutescens: The story of an enigma

Vogel

Jainta

Rau

et al. 1998

Cytogenet Genome Res

View full text Add to dashboard Cite

The unusual karyotype of Ellobius lutescens (2n = 17,X in males and females) has attracted permanent interest and prompted a series of hypotheses on sex determination in this species since its first description by Matthey (1953). The developing knowledge about the sex chromosomes and sex determination as well as the availability of new cytogenetic and molecular genetic techniques prompted studies to test the compatibility between current hypotheses and new findings and rendered modifications of the hypotheses necessary. After a long period dominated by the question what the sex chromosome constitution of this species might be and where the testis determining factor could be located, the presence of Sry had been eventually excluded and sex determination attributed to a hypothetical mutated gene acting downstream of Sry. An X-chromosomal or autosomal location of this gene can be assessed by cosegregation of sex with X-chromosome markers. Some preliminary results concerning X-chromosome dinucleotide repeat markers are reported. However, these markers were homomorphic in Ellobius lutescens. We now report evidence that Zfy is also missing in Ellobius lutescens and E. tancrei (males and females XX), a finding from which we conclude that the entire Y chromosome has been lost from these species. Perspectives concerning future studies are discussed.

show abstract

“…The X remains un paired at meiosis. Meiosis and spermatogenesis are maintained without a Y chromosome (Castro-Sierra and Wolf, 1968;Chandra, 1999). The mammalian sex-determining gene SRY is absent in XO species of Ellobius (Kuroiwa, 2012).…”

Section: Geneticsmentioning

confidence: 99%

Review of unique odd chromosome-numbered underground rodent species ofthe Palearctic region: Ellobius lutescens Thomas 1897 (Rodentia: Cricetidae)

Coşkun¹

2016

Turk J Zool

View full text Add to dashboard Cite

A review of the species within the genus Ellobius from Turkey is provided. The Transcaucasian mole vole, Ellobius lutescens, is the westernmost representative of the genus and among the most enigmatic and yet most neglected of the Palearctic placental mammals. Currently, its distribution is thought to be restricted to eastern Anatolia. The Transcaucasian mole voles inhabit a wide variety of habitats across this distribution area in semiarid or grassland territories and high-elevation cultivated fields. The species' distribution, feeding ecology, population structure, behavior, reproduction, genetics, and fossil records are reviewed here for Turkey. This paper brings together information published during the last century in books and scientific papers. Future research needs to include collation of further data on population dynamics, maximum length of the breeding season, reliable abundance estimates, and studies of distribution and migration. Other areas worthy of investigation are the identification of wintering areas, acquisition of up-todate data on reproduction and mortality, and investigations into the consequences of environmental changes for the species.

show abstract

Studies on the male meiosis of <i>Ellobius lutescen</i><i>s</i> Th.

Cited by 23 publications

References 2 publications

The sex determination in <i>Ellobius lutescens</i> remains bizarre

The sex determination in <i>Ellobius lutescens</i> remains bizarre

Sex determination in <i>Ellobius lutescens:</i> The story of an enigma

Review of unique odd chromosome-numbered underground rodent species ofthe Palearctic region: Ellobius lutescens Thomas 1897 (Rodentia: Cricetidae)

Contact Info

Product

Resources

About