Studies on the in vivo hypoglycemic activities of two medicinal plants used in the treatment of diabetes in Jordanian traditional medicine following intranasal administration

Afifi, Fatma U.; Alkhalidi, Bashar A.; Khalil, Enam A.

doi:10.1016/j.jep.2005.03.016

Cited by 53 publications

(27 citation statements)

References 50 publications

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“…In Damascus, it is one of the main botanical components of multi-herbal tea "Zahraa," usually recommended as the after meal tea to promote good health (Carmona et al, 2005). Subjected to scientific scrutiny, P. argentea showed significant α-amylase inhibitory activity in vitro but not a significant hypoglycemic activity in STZ-diabetic rats or alloxan diabetic rabbits (Afifi et al, 2005). Braca (2008) had extensive spectroscopic and spectrometric analysis for P. argentea isolating and characterizing two oleanane saponins, one flavonol glycoside, and six flavonoids.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the acute antihyperglycemic effects of four selected indigenous plants from Jordan used in traditional medicine

Kasabri

Afifi

Hamdan

2011

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 99%

Evaluation of the acute antihyperglycemic effects of four selected indigenous plants from Jordan used in traditional medicine

Kasabri

Afifi

Hamdan

2011

Pharmaceutical Biology

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“…Charaka Samhita and Sushruta Samhita gave an extensive description on the treatment of diabetes with medicinal herbs (Ali Hussain, 2002), which is regarded as a noncurable but controllable disease (Schoenfelder et al, 2006). Several authors reviewed the potential role of medicinal plants as hypoglycemic agents, which is supported by various ethnobotanical surveys (Roy & Agrawal, 2001;Li et al, 2004;Afifi et al, 2005). Such study might provide a natural key to unlock a diabetologist's pharmacy for the future.…”

Section: Discussionmentioning

confidence: 99%

Hypoglycemic and Antihyperglycemic Activity of Nymphaea stellata Flowers in Normal and Alloxan Diabetic Rats

Rajagopal

Sasikala²,

Ragavan³

2008

Pharmaceutical Biology

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Flowers of Nymphaea stellata Willd. (Nymphaeaceae) are used in the Indian traditional system of medicine to treat diabetes mellitus but have not been scientifically investigated. Hence, the current study was aimed to evaluate the hypoglycemic and antihyperglycemic effect on normal and alloxan-induced diabetic rats. Hydroethanol extract (HEE) of Nymphaea stellata at an oral dose of 200, 300, and 400 mg/kg was given, and blood glucose level (BGL) on normoglycemic and, diabetic rats and oral glucose tolerance test (OGTT) were evaluated. HEE of the flowers did not show significant reduction on BGL in normoglycemic rats but significantly (p < 0.001) reduced the BGL in hyperglycemic animals by improving OGTT. These results clearly show that flowers of N. stellata do not have hypoglycemic activity in normoglycemic rats but have an antihyperglycemic activity in alloxan-induced diabetic rats.

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“…It is regarded as a non-curable but controllable disease. [2] Diabetes mellitus is characterized by increased concentration of blood glucose due to derangement in carbohydrate metabolism and defective insulin production. The metabolic disturbances results in acute and long term diabetic complications.…”

Section: Aim and Objectivementioning

confidence: 99%

Evaluation of Foeniculum Vulgare and Tagetes Erecta for Synergic Anti Diabetic Activity in Streptozotocin Induced Diabetic Rats

Basha¹

2017

WJPR

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Herbal medicine sometimes referred to as Herbalism or Botonical medicine it includes use of herbs for treating pathological condition in the system. Herbal medicine have received considerable attention during last two decades as they are endowed with variety of biological activities and have wide range of therapeutic properties. Diabetes mellitus (DM) is the name given to a multiple group of disorders with different etiologies. It is characterized by derangement in protein, carbohydrate, and fat metabolism caused by the complete or relative insufficiency of insulin secretion and/or insulin action. Diabetes is a major health problem worldwide as approximately 5% of the world's population suffers from diabetes. Diabetes is a multifaceted disease involving impaired insulin secretion and insulin resistant. The loss of glycemic control, associated with these defects results in long-term complications which are both micro vascular (e.g.; retinopathy, nephropathy, neuropathy) and macro vascular (e.g.; stroke, myocardial infraction and peripheral vascular disease). The current treatment for both of diabetes delay, but do not prevent the micro vascular disease, leading in the long run to complications, including heart disease, stroke, blindness, kidney failure and limb amputation. Traditional plant medicines are used throughout the world for a range of Diabetic presentations. Therefore, investigation on such agents from traditional medicinal plants has become more important. India has a rich history of using various potent herbs and herbal components for treating Diabetes. Many Indian plants have been investigated for their beneficial use in different types of Diabetes. Foeniculum vulgare belonging to family Umbelliferae is mainly used as a food condiment the chief chemical constituent of fennel is volatile oils but it also contain ketone, fenchone, phellladrine.Pharmacologically it is used as anti-inflammatory, anti-oxidant, and hepatoprotective.

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Studies on the in vivo hypoglycemic activities of two medicinal plants used in the treatment of diabetes in Jordanian traditional medicine following intranasal administration

Cited by 53 publications

References 50 publications

Evaluation of the acute antihyperglycemic effects of four selected indigenous plants from Jordan used in traditional medicine

Evaluation of the acute antihyperglycemic effects of four selected indigenous plants from Jordan used in traditional medicine

Hypoglycemic and Antihyperglycemic Activity of Nymphaea stellata Flowers in Normal and Alloxan Diabetic Rats

Evaluation of Foeniculum Vulgare and Tagetes Erecta for Synergic Anti Diabetic Activity in Streptozotocin Induced Diabetic Rats

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