Studies on the evaluation of the toxicity of various salts of lead, manganese, platinum, and palladium.

Holbrook, David; Washington, Mildred E.; Leake, Hansford B.; Brubaker, Paul E.

doi:10.1289/ehp.751095

Cited by 59 publications

(10 citation statements)

References 4 publications

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“…Toxicity of metal catalyst salts toward rats via ingestion is taken from MSDS and literature sources. − Similar to the method previously mentioned, LD 50 values for salts are chosen to being the most unfavorable.…”

Section: Methodsmentioning

confidence: 99%

Ranking of Heterogeneous Catalysts Metals by Their Greenness

Bystrzanowska

Petkov

2019

ACS Sustainable Chem. Eng.

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Catalysis is a very important process in industry and laboratory practices, especially from the point of green chemistry principles. However, the eco-friendly character of heterogeneous catalysts containing transition-metal components has not yet been evaluated. Therefore, we performed a comprehensive assessment of 18 heterogeneous metal catalysts (Pd, Pt, V, Co, Ni, Mo, Ru, Mn, Au, Cu, Cd, Zr, Fe, Rh, Ir, Sn, Zn, Ag) using a multicriteria decision analysis approach. The ranking of alternatives according to relevant criteria, such as the toxicity of pure metals and metal salts toward fish, Daphnia magna, and algae/plants, metal toxicity toward rats via ingestion, carcinogenicity, the endangerment degree of metals, the boiling point and energy for atom detachment (estimated as metal–metal bond strength in diatomic transition-metal units), and the classification of elemental impurities according to the International Conference on Harmonization, and their degree of importance are presented. Life cycle assessment (LCA)-related parameters of metals have been also included. The assessment showed ruthenium, iron, and molybdenum as the most favorable alternatives, in contrast to nickel, cobalt, and rhodium. Results of environmental evaluation strictly depend on the chosen scenario of assessment, in terms of toxicity, endangered elements, or LCA. Sensitivity analyses toward variations in input data and applied weights prove that the results are reliable. Multicriteria decision analysis can be successfully applied in metal catalyst evaluation for particular case studies of different reactions.

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Section: Methodsmentioning

confidence: 99%

Ranking of Heterogeneous Catalysts Metals by Their Greenness

Bystrzanowska

Petkov

2019

ACS Sustainable Chem. Eng.

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“…(424) The fractional absorption of palladium, administered as the chloride, from the gastrointestinal tract of adult rats is <5 Â 10 À3 (Moore et al, 1974(Moore et al, , 1975b. Acute toxicity data from experiments on rats indicate that the fractional absorption of palladium administered as PdO or PdSO 4 is even smaller than that of the chloride (Holbrook et al, 1975).…”

Section: Ingestionmentioning

confidence: 99%

“…(589) Information regarding the detection limit for routine individual measurement is not available. , 1981), a fractional absorption value of 0.01 was recommended for all chemical forms of platinum based on the animal studies by Moore et al (1975) and Holbrook et al (1975). This value was also adopted in Publication 68 (ICRP, 1994a).…”

Section: Individual Monitoringmentioning

confidence: 99%

ICRP Publication 151: Occupational Intakes of Radionuclides: Part 5

Paquet¹,

Leggett²,

Blanchardon³

et al. 2022

Ann ICRP

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“…In animals, the lack of Mn can result in impaired insulin production, alterations in lipoprotein metabolism, impaired oxidant defense system, and perturbations in growth factor metabolism (for review see Keen et al, 1999). When rats are treated orally with high doses of Mn salts, retention of excess concentrations of Mn are not detectable after 14 days in any tissue suggesting that the rate of accumulation and overall toxicity of Mn is rather low (Holbrook et al, 1975). In line with that assumption, confirmed cases of Mn toxicosis in humans are currently restricted to cases of exposure to high levels of airborne Mn, and to cases in which Mn excretory pathways are malfunctioning (Keen et al, 1999).…”

Section: Hepatic Manganese Contentmentioning

confidence: 99%

Trace metal imaging in diagnostic of hepatic metal disease

Susnea

Weiskirchen

2015

Mass Spectrometry Reviews

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The liver is the most central organ and the largest gland of the body that influences and controls a variety of metabolic and catabolic processes. It produces inconceivable many essential proteins, is responsible for the recovery of various food components, degrades toxins, mediates the bile production, and is involved in the excretion of unwanted metabolites. Several of these anabolic or catabolic functions of the liver depend on trace elements. These are either integral part of enzymes, cofactors, or act as chemical catalysts. Therefore, a lack of trace elements can lead to organ failure or systemic illness. Conversely, excessive hepatic trace element deposition resulting from genetic disorders, intoxication, extensive dietary supply, or long-term parenteral nutrition may cause hepatic inflammation, fibrosis, cirrhosis, and even hepatocellular carcinoma. Although specific serum parameters currently allow rough assessment of metal deficit and excess, the precise quantification of hepatic metal content in liver is presently only possible by different titration or staining techniques of biopsy specimens. Recently, novel innovative metal imaging techniques were developed that are on the way to replace these traditional methods. In the present review, we summarize the function of different trace elements in liver health and disease and discuss the present knowledge on how quantitative biometal imaging techniques such as synchrotron X-ray fluorescence microscopy, secondary ion mass spectrometry, and laser ablation inductively coupled plasma mass spectrometry enrich diagnostics in the detection and quantification of hepatic metal disorders. We will further discuss sample preparation, sensitivity, spatial resolution, specificity, quantification strategies, and potential future applications of metal bioimaging in experimental research and clinical daily routine. © 2015 Wiley Periodicals, Inc. Mass Spec Rev 35:666-686, 2016.

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Studies on the evaluation of the toxicity of various salts of lead, manganese, platinum, and palladium.

Cited by 59 publications

References 4 publications

Ranking of Heterogeneous Catalysts Metals by Their Greenness

Ranking of Heterogeneous Catalysts Metals by Their Greenness

ICRP Publication 151: Occupational Intakes of Radionuclides: Part 5

Trace metal imaging in diagnostic of hepatic metal disease

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