Studies on the Development and Chemotherapy of Larvae of Parascaris equorum (Nematoda: Ascaridoidea) in Experimentally and Naturally Infected Foals

Et, Lyons; Jh, Drudge; Sc, Tolliver

doi:10.2307/3279157

Cited by 42 publications

(9 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fecal samples were collected on the day of treatment and at 7 (most >7) to 14 days after treatment. Search for ascarid and strongyle eggs in feces of foals was by a qualitative method (presence or absence) or a quantitative method (eggs per gram of feces-EPGs; Lyons et al 1976Lyons et al , 1988. A qualitative examination for parasite eggs was made on all fecal samples except those from foals on Farm KY in which a quantitative method was used.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007

et al. 2008

Self Cite

View full text Add to dashboard Cite

Horse foals on five farms in Central Kentucky were used in field studies in 2007 evaluating activity of paste formulations of four compounds (fenbendazole-FBZ, ivermectin-IVM, oxibendazole-OBZ, and pyrantel pamoate-PRT) against internal parasites with emphasis on ascarids (Parascaris equorum). It has been well established the last few years that there is widespread resistance of P. equorum to ivermectin. The main purpose of the present research was to obtain current data on ascaridicidal activity of FBZ, OBZ, and PRT; also, to acquire further information on ascarid resistance to ivermectin. Additionally, data were documented on drug activity on small strongyles. Detection of ascarid and strongyle eggs in feces of foals was by a qualitative method (presence or absence) or a quantitative method (eggs per gram of feces). Strongyle eggs all were assumed to be from small strongyles. This is based on fecal cultures from horses on one farm and historic records from horses in this area on excellent deworming programs. A girth tape was used to estimate the body weight of each foal so that the appropriate dose rate of each drug could be given. Many of the foals were used in more than one cycle of treatments. Efficacy of the drugs, administered intraorally, was determined by calculating the average percentage reduction (% red.) of the number of foals passing eggs after vs. before treatment: (1) FBZ at 10 mg/kg was tested on four farms; 76 foals were examined, 50 with ascarid eggs (84% red.) and 62 with strongyle eggs (0% red.); (2) IVM at 200 microg/kg was tested on three farms; 58 foals were examined, 18 with ascarid eggs (0% red.) and 48 with strongyle eggs (100% red.); (3) OBZ at 10 mg/kg was tested on three farms; 181 foals were examined, 78 with ascarid eggs (94% red.) and 79 with strongyle eggs (0% red.); (4) PRT was tested on two farms, one farm at 1x (6.6 mg base/kg); 42 were foals examined, 16 with ascarid eggs (0% red.) and 33 with strongyle eggs (12% red.) and one farm at 2x (13.2 mg base/kg); 18 foals were examined, 13 with ascarid eggs (23% red.) and 15 with strongyle eggs (27% red.).

show abstract

Section: Methodsmentioning

confidence: 99%

Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007

et al. 2008

Self Cite

View full text Add to dashboard Cite

show abstract

“…Sheather's solution was used mainly because it has a specific gravity high enough for excellent flotation of Eimeria leuckarti oocysts. The qualitative technique was used because it is much more sensitive for detecting oocysts and nematode eggs, especially when present in low numbers, than is the quantitative modified Stoll technique (with a factor of 10), which the authors (Lyons et al 1976) used for determining worm eggs per gram of feces (EPGs). This qualitative method, which concentrates oocysts and nematode eggs, is important for assessing not only the effect of parasiticides but also the prevalence of parasites.…”

mentioning

confidence: 99%

Field studies on endoparasites of Thoroughbred foals on seven farms in central Kentucky in 2004

2005

Self Cite

View full text Add to dashboard Cite

Fecal samples (n=1,584) for a parasite study were collected from Thoroughbred foals (n=349), 28 to 330 days old, on seven farms in central Kentucky during 49 monthly trips from May to October, November, or December 2004. The main purpose was to determine possible drug resistance of ascarids, also of strongyles, to ivermectin (IVM) and other commercially available compounds [fenbendazole, moxidectin (MOX), oxibendazole (OBZ), and pyrantel pamoate]. In addition, interest was on prevalence of foal parasites. Qualitative data were obtained by recording presence or absence of ascarid and strongyle eggs in feces from 7 to 25 days after treatment of some of the foals. None of the compounds completely eliminated ascarid eggs in feces of all foals posttreatment. Activity on ascarids was significantly the highest for OBZ and lowest for IVM. Activity on strongyles was significantly higher for IVM and MOX than for the other compounds. Prevalence (mean percentage of foals infected) was recorded for eggs of Parascaris equorum (39%), of strongyles (32%), and of Strongyloides westeri (2%) and oocysts of Eimeria leuckarti (28%) in feces of foals. One or more foals had infections of P. equorum on six farms (86%), strongyles on seven farms (100%), S. westeri on two farms (29%), and E. leuckarti on six farms (86%). The oldest foal infected with E. leuckarti was 301 days of age. Comparison was made on the prevalence of parasites in foals on five of the same farms in the 2004 study, which were part of a similar 14-farm project in 2003 (Lyons and Tolliver in Parasitol Res (2004) 92:400-404).

show abstract

“…Regular manure removal from the pastures and systematic rotation of horses in paddocks and pens is recommended (Lyons et al 1976). Yearly coprological examination is recommended to assess the efficacy of the management procedures (Kaplan 2002).…”

Section: Discussionmentioning

confidence: 99%

Monitoring the avermectin and pyrantel resistance status of nematode parasites of horses in the Czech Republic

Bodeček¹,

Svetlikova²,

Hargitaiova³

et al. 2018

Vet. Med. - Czech

View full text Add to dashboard Cite

ABSTRACT:The avermectin and pyrantel resistance of equine parasites was monitored on four farms in the Czech Republic in 2014. The aim of the testing was to investigate the anthelmintic resistance of cyathostomins and ascarids. One hundred and eighty-six horses were included in the test, 54 of which were infected by ascarids and 174 by cyathostomins. Faecal egg count reduction tests were used to assess anthelmintic resistance. The faecal egg count reduction for ascarids was within the range of 87.9% to 100% for avermectins and 100% for pyrantel embonate. Faecal egg count reduction for cyathostomins ranged from 99% to 100% for avermectins and 89.3% to 98.2% for pyrantel embonate.

show abstract

Studies on the Development and Chemotherapy of Larvae of Parascaris equorum (Nematoda: Ascaridoidea) in Experimentally and Naturally Infected Foals

Cited by 42 publications

References 4 publications

Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007

Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007

Field studies on endoparasites of Thoroughbred foals on seven farms in central Kentucky in 2004

Monitoring the avermectin and pyrantel resistance status of nematode parasites of horses in the Czech Republic

Contact Info

Product

Resources

About