Abstract:Two strains of the lymphogranuloma venereum virus were maintained in tissue cultures for 12 and 21 generations respectively.
In a third strain a quantitative increase in potency as high as 1000 times was obtained by inoculating tissue cultures with infected emulsions of known virulence.
Greater increases in potency were consistently obtained by maintaining tissue cultures and virus at room temperature (23°C. with a range of approximately ± 5°C.) than by incubating them at 37°C. Th… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.