Studies on the Cardiopulmonary Function in Sarcoidosis Iii

On the Influence of Body Position on Steady‐state Diffusing Capacity during Exercise, Studied in Patients with Pulmonary Sarcoidosis

“…The case histories were similar to those earlier reported (16,33,34) with dyspnoea, orthostatic complaints and tiredness as major symptoms.…”

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In earlier studies (16,33,34) on the steady-state diffusing capacity of the lungs for carbon monoxide, D L~~, in patients with pulmonary sarcoidosis, a low DL~. was observed in all stages

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“…The material consists of 12 patients with pulmonary sarcoidosis, 10 women and two men, aged from 28-49 years. Eight of the women had bilateral hilar lymphomas only (group I) (16,33,34). Case 1 had minor parenchymal infiltrations (group 11) and case 8 had minor infiltrations plus roent-genological signs of fibrosis (group 111).…”

“…O n the basis of the normal regression between DL~. during exercise at heart rates above 120 beat per minute and total hemoglobin (THb) (12), the ma-Submitted for publication November 12, 1965. terial reported earlier (16,33,34) was analyzed with regard to whether a marked postural increase in heart rate at rest or during exercise was accompanied by low D L~~ during exercise in the sitting position ( fig. 1).…”

Pulmonary Function in Patients with Endobronchial Sarcoidosis

“…Cough, phlegm, wheezing and dyspnoea are common symptoms in patients with bronchostenosis due to sarcoidosis (1, 2). Airway obstruction in sarcoidosis has earlier been attributed to pulmonary fibrosis (3,4) but has also been reported in patients with endobronchial sarcoidosis (5) and stage I sarcoidosis (6). Restrictive spirometry pattern seems to be more common in patients with stage I1 than stage I sarcoidosis (4).…”