Studies on the Biological Activity of Nicotinic Acid N-Oxide. II

Tazaki, Hiroshi; Kanamitsu, Osamu

doi:10.1248/yakushi1947.81.12_1754

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2009

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Cited by 5 publications

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“…It is interesting that the cytosolic aldehyde oxidase can mediate NAD(P)H-sustained nicotinamide N-oxide reduction when combined with the microsomal NADPH-cytochrome c(P-450) reductase (EC 1.6.2.4) redox protein 162 . Similarly, nicotinic acid N-oxide has been found to be reduced in vivo after an oral or intravenous dose to rats, and this activity was associated with the hepatic cytoplasm 163 .…”

Section: Reductionsmentioning

confidence: 96%

N‐Oxidative Transformations ofCNGroups as Means of Toxification and Detoxification

Hlavica

Lehnerer

2009

Patai's Chemistry of Functional Groups

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Introduction Chemical Aspects of the N ‐Oxygenation of the C  N Functionality Occurrence of N ‐Oxygenated C  N Functionalities in Natural and Synthetic Compounds and Biological Activity Metabolic in Vivo and in Vitro Formation of N ‐Oxygenated C  N Functionalities Enzymology of the Formation of N ‐Oxygenated C  N Functionalities Further Transformations of N ‐Oxygenated C  N Functionalities Conclusions

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Section: Reductionsmentioning

confidence: 96%